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""The CD4+ T cells are of particular interest"""", as coadministration of CD4+ T cells to TCR-engineered adoptively administered T cells has been shown to enhance tumor infiltration of CD8+ T cells and to prevent their exhaustion """
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485745/
he likes CD4 ....
ATB
Inanaco,
Thanks so divisional nucleic acid patent is unrelated to TCRs - thanks. Still don't understand how they can encode the DNA and insert into viral vector without nucleic acid protection but way beyond me and I don't need to. Just wanted to establish whether or not the divisional was connected and you've clarified so thanks.
When you get a chance - can you explain what the screening patent is for then? I know how it works but is it just for TCRs? Or is it just part of the process of selecting the best cit. epitopes for any use?
again show the link Bermuda ... if you asking for specifics .. and i will have a read ....
but also read this
https://www.nature.com/articles/nature14426?page=7
dated 2015
its about time Burble had a coffee break and posted some stuff on here ...
i am sure we could all contribute to his coffee welfare fund ...
Inanaco,
Nobody needs the specifics thanks. Was simply 2 questions:-
1) Does nucleic acids divisional cover TCRs
2) What is the screening divisional patent all about - not what it does but how it is used, what it it's application?
You've confirmed the answer to no. 1 is no and at some stage would appreciate any light you're able to throw on no. 2.
link ...= comment
trying to catch up on the BBC news ref statements
those predictions look very real ....
and if true ......... especially ref the antibodies ... Puts Scancell in an unbelievable position because we are building a vaccine today ... not based on just the genome of the virus as it was in January
nightmare ... upgraded my phone to Voice over internet ... BT cut of the old line without saying .. so just had to study the new phone ... smart kit the new phone is awesome ... and worked instantly including a very flash clock displayed
You've confirmed the answer to no. 1 is no and at some stage would appreciate any light you're able to throw on no. 2.
please provide link
Inananco, - a link to what? To the screening patent? If so it's below. No hurry, just when you get a chance.
https://register.epo.org/application?number=EP17194252
read page 14 .................. of the description .. OMG
https://register.epo.org/application?documentId=E47EAZPI5402DSU&number=EP17194252&lng=en&npl=false
some of the epitopes can be used for "suppression" .....
page 26 ...
"human vimentin " tested in mice
page 27 ... immunized via gene Gun ... (DNA)
Bermuda for your bit .. ref screening read from page 56
wild ............ an OMG from me indicates excitement and another billion dollar target ..
all those that had sold or top sliced .. and not spent the cash ... are now diving back in .. MM know it .. tick tock next run at 18p ..
"delayed Buys" are back ............
Inanaco will do.
Think we should clarify that these patents only cover cancer but as you have highlighted, Scancell have only scratched the surface of the potential of Moditope. The sooner those trials get underway the better.
so page 58 number 15 gives a description ... of how they screen so i suggest its something developed in house these arginine residues
i cannot cut and paste from these PDF links
Well I read it and understand what they're doing but afraid I still don't understand how it fits into the bigger picture. No matter.
Land Grab ...
£8 a share .......... is very real
agreed. think penicillin.