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A clip from nanaco “moditope has passed phase 1 and is showing positive signs”
Is this for real ? No wonder big Pharma don’t show any sign of interest
Violin, Sadly only telling It as I see It. Who and Why the consistent selling?. Unfortunately topped up at the last dilution. Fortunately Not a lot. Last placing @ 11P today's SP 9.50P IMO.
Good find Cleaner. I see that this relates to the partnership with Vaccitech announced 7 November’22. I wonder if we will have a Phase 1 study this year:-
https://www.lse.co.uk/rns/SCLP/licenses-vaccitech-technology-to-advance-modi-2-5arpm4twcqxzkuu.html
Prof Lindy Durrant, Chief Executive Officer, Scancell, commented: "We are pleased to partner with Vaccitech to take the second candidate from our Moditope® platform through GMP and subsequent clinical development. With its elegant and effective solution, the SNAPvax™ technology provides an excellent method for formulation of the Modi-2 vaccine. Combining this technology with our expertise will allow us to develop a rapid manufacturing process for Modi-2, with the hope that we can bring it into a Phase 1 clinical study during 2024."
If no value why pay $200m ? It seems scan is good in posters and repeating ample times the same message.
Burn cash and next round of dilution will be lower than the 11p. If concrete then give up some info if not stop promoting a dream by claiming encouraging promising exciting and the rest of wishful thinking outcome. And please take if hope and other BS descriptive words from future communication
wednesday 7 th of august 11:25 am
modi-2, a vaccine targeting ****citrullinated self-epitopes, stimulates potent cd4-mediated anti-tumor responses as a therapy for solid cancers
https://www.immuno-oncologysummit.com/cancer-vaccines?utm_source=linkedin&utm_medium=social&utm_campaign=vjm_final_track_agenda_20240423
abdullah al-omari, phd, scientist, t cell vaccine, scancell ltd.
stresses within the tumor microenvironment mediate post-translational modifications of self-proteins. ****citrullination is the conversion of lysine residues to ****citrulline which can generate neoepitopes and bypass self-tolerance. modi2, a ****citrullinated peptide-snapvax vaccine, stimulates strong th1 responses and anti-tumor immunity in three different murine tumor models. we propose the modi-2 vaccine formulation has potential for translation into clinic in several cancer indications.
Drac, you are correct re the sales..as for Redmile...whatever raises the SP...nothing else is achieving this, even after the numerous conferences.
A whiff of desperation (i.e. ill thought out comments ) in quite a few posts of late IMO.
Interesting.
I think even you known the answer to that Dracula.
You'll have to try a lot harder to bridge your credibility gap.
With No interest. Will the big Investors take Sclp private for say a low ball offer of say £200 Ml ?.
Nothing new at all, from “AI Powered Pharmaceutical Intelligence”
Https://synapse.patsnap.com/drug/ceab59ba703544a2a1d8c8da9b59e11a
Doesn't surprise me, but these are generic titles so may present a more broad overview of cancer vaccines in the melanoma space. Especially as they cover different patient demographic groups.
Thanks for that Burble. I think she's also an investigator for the Moderna mRNA vax.
It seems she also presented at the Association of Cancer Physicians event on the 1st March 2024 in the New Therapies session delivering a presentation titled 'cancer vaccines: trials and the future - where are we now?' Interesting tweet about it https://x.com/drlennardlee/status/1763629978430669099 'There was spontaneous applause when we heard what she was achieving in the #cancervaccine space!'
Ruck
Just to remind you
Sheffield United 1 Burnley 4
Bring on Man United next 😀
Bermuda,
Dr Shaw is also presenting at the Oncology Forum (https://oncology-forum.co.uk/wp-content/uploads/2024/04/2024-UK-Oncology-Forum_DRAFT-Programme-4.pdf) in a breakout session titled 'multidisciplinary challenges for modern melanoma clinical practice' with a half hour talk entitled 'vaccines in early and advanced melanoma'.
This meeting is only open to UK cancer healthcare professionals, and has breakout sessions for the main cancer types.
TF,
I must have blocked that from my memory as half the family are big SUFC fans. UTB
Yes Ruck and good for them ! What a fine result Burnley had, walloping Sheffield United the other day. Come on Burnley !
Really good to see that Heather Shaw, one of the SCIB1 study investigators will be presenting a poster at ASCO in Chicago in June. The abstract title:-
A DNA plasmid melanoma cancer vaccine, SCIB1, combined with nivolumab + ipilimumab in patients with advanced unresectable melanoma: Efficacy and safety results from the open-label phase 2 SCOPE trial.
Presenter: Heather May Shaw, MD, FRCP, MRCP | Mount Vernon Cancer Center
Abstract: 9535
| Poster Bd #: 319
ASCO isn't just another scientific conference, it's the largest oncology conference in the world and it would have been disappointing if Scancell were not represented.
https://meetings.asco.org/meetings/2024-asco-annual-meeting/316/program-guide/search?q=
"True, but it's nice to have some goals in life I suppose."
Don't rub it in ratty, some people here support Burnley.
WTP - I think that Sath was a 'Panel member' rather than 'Presenting'. But hopefully he had some useful interactions anyway!
It feels like 'all hands on deck' and the 'quiet' is a bit strange. Who knows what's afoot, or not?
@Dalester + Jambion + Burble. Wondering the same sort of thing. These conference attendances would have confirmed months and months ago you'd think, so obligated to attend?
Also, very odd that the CFO went to present what was a scientific presentation?
Hi jb. Again.
I don't see your response as a fair comment. Reconsider - one might wish to make a contribution, i.e. something other than understandable but never ending observation of the 'long' wait for news. That's it. Have fun. BFN
I ost infrequently for a reason. Not to bore the pants of others with other people's messages.
We know that there were companies wanting exclusivity for some of the Mabs, so we could easily conclude thst they would want an NDA too. Attending conferences also gives some, cover for meetings too. Better for everyone if the NDA covers as wide an area as possible, so perhaps we have been attending pre-booked conferences or ones where being there for some private discussions was important, but being very mindful of not letting new information slip out so stick to an old script..
So all new info is under blackout conditions until such time as an agreement is reached or negotiations fail... the bigger the deal / s the longer the negotiations, the longer the NDA will last.... well its a theory!