We would love to hear your thoughts about our site and services, please take our survey here.
London South East prides itself on its community spirit, and in order to keep the chat section problem free, we ask all members to follow these simple rules. In these rules, we refer to ourselves as "we", "us", "our". The user of the website is referred to as "you" and "your".
By posting on our share chat boards you are agreeing to the following:
The IP address of all posts is recorded to aid in enforcing these conditions. As a user you agree to any information you have entered being stored in a database. You agree that we have the right to remove, edit, move or close any topic or board at any time should we see fit. You agree that we have the right to remove any post without notice. You agree that we have the right to suspend your account without notice.
Please note some users may not behave properly and may post content that is misleading, untrue or offensive.
It is not possible for us to fully monitor all content all of the time but where we have actually received notice of any content that is potentially misleading, untrue, offensive, unlawful, infringes third party rights or is potentially in breach of these terms and conditions, then we will review such content, decide whether to remove it from this website and act accordingly.
Premium Members are members that have a premium subscription with London South East. You can subscribe here.
London South East does not endorse such members, and posts should not be construed as advice and represent the opinions of the authors, not those of London South East Ltd, or its affiliates.
Charts are total rubbish. You can make read however you want !
Give it a rest Winne
Yesterday's price action was a doji formation. (ohlc), (opened, went up and down and closed at the same price as it opened)
In itself its a common enough one day pattern, but if we close up today then it would indicate a reversal, with yesterday's Doji suggesting a bottom had formed.
This was/is much more relevant in day trading and scalping smaller moves, but with the RSI supporting at least a bounce then there are very tentative signs of a reversal here , but this is very much at the "possible" (or maybe straw- grasping) stage of a turn around.
Targetting directly into the tumour reduces damage to other organs, nasty side effects and allows for higher dosing...
The first too add huge value for patients...the latter if it leads to faster cancer cell death is a huge bonus.
What is not to like...?
One in Two get cancer nowadays...derampers are not immune and to try and take down a company try to find a better method of administering these very toxic chemo drugs is not a good look...
Blaming Avacta for your own investment decisions is soooo dumb...
They need to get paid they spend a fortune on pom poms.
I think rah and tom are paid rampers . Say anything negative and your blocked
Open Short Positions in Avacta Group
Fund.............................. % Short Change Date Changed
Gsa Capital Partners Llp 0.50%... 0.00%.... 16 Apr 2024
Total 0.50%
I refer you to my posts after the December briefing in which I questioned rate of AVA6000 cleaving versus rate of cleaved fox being excreted. The AVA6000 half life in the bloodstream is very short. I said that I thought the variable results in patients was a strong reason to delay P1a to insert a 2 weekly trial in the expectation that this would improve results to the extent that BP or IIs would be convinced enough to invest.
The Pom Pom girls poo pood this suggestion but I still feel that this was the main reason for the change in strategy. I think and hope that arm2 will give us the results we need but it is far from being a slam dunk and that is why we are where we are.
Al is the king of the ambiguous communication especially if it allows him to big up the prospects of Avacta. You have only yourselves to blame if you chose to read Al’s words in the best possible light and then over invest.
How chart experts see it.
https://www.barchart.com/stocks/quotes/AVCT.LN/overview
Barchart Technical Opinion
STRONG SELL
The Barchart Technical Opinion rating is a 100% Sell with a Strengthening short term outlook on maintaining the current direction.
Long term indicators fully support a continuation of the trend.
The market is approaching oversold territory. Be watchful of a trend reversal.
I think RAH and Tom are one in the same. Their doctors really need to reduce their uppers because they really focus on the up with RAH occasionally claiming he has bought 15000 more!
Clearly: more ava6000, more cleavage, more dox, more cancer cells disrupted
I’m sure: if any competent scientist were performing a trial, they would ensure that the data collected would inform them on the effects of increased dosing. Such as the half life of the dose. They wont be making decisions in a vacuum.
Not trying to win any arguments here, just trying to make logical sense of it all.
It’s abundantly clear, and has been for a while, be it with this example or countless others, that the likes of RAH, Myles and perhaps some others are using their influence amongst PI’s to their own personal gain. Amazing PI’s haven’t woken up to this.
Is this the Fud argument these days haha Al going nowhere the social media witch hunt doesn’t represent the vast majority of Pi’s. 🤣🤣
as you say, pair of em called the sum total of **** all correct.
'Clearly' and 'I'm sure'.
That's an argument well won then Gje.
If you trust in the Science why excellent.
The darkest hour....
RAH and Tom the bomb seemingly suggesting that Alan is on his way out. Their track records are appalling so I’m not getting my hopes up too much before bed but I thought I’d share this potentially excellent news.
Clearly increasing dose frequency will increase the efficacy, and they can keep on increasing the frequency beyond 2 weeks exactly because it has been shown to be safe. I'm sure they have already calculated and identified that 2 weeks will deliver the results they're after. Once approved, all other combinations can be tried out by clinicians as they build up their knowledge of this drug.
As for the backers... we had first hand evidence that there are plenty who backed the raise with absolutely no clue of the underlying science.
Going to single digits before your very eyes!!!
DUMB MONEY!!!
Just look at the SP typical AIM the Board getting rich while PI's foot the bill!!!
Why keep saying ,AS Is a great Scientist!!
What evidence of that do you have?
He ,has bought in so many science backed deals to Avacta .
That all proved to be commercial duds.
If he is such a scientific genius?
You would think he may know better!!!
Yes a half life extension process should make it better (?)
But is it good enough without it.
Who knows?
Well, I suspect they do.
And those who backed the raise.
At 50p.
I'd say most of it is excreted, given the half life of ava6000, but that's not the important bit here, it's actually how much is converted and concentrated in the tumour, and the answer from the biopsies is there is enough to be therapeutic. The excretion of the majority of it is a necessary part of the process. If you consider that in order to get a sufficient concentration to the tumour through the bloodstream, it is a requirement to raise the levels of AVA6000 throughout the body. Only the AVA6000 that happens to pass by the tumour will be cleaved. The excreted AVA6000 represents all the dox that would otherwise be absorbed by healthy tissue, so it's an overwhelmingly positive thing.
Roll on the half life extending serum they're working on and one can only imagine the boost to efficacy.