Sareum Regulatory News (SAR)

SAREUM HOLDINGS PLC

("Sareum" or the "Company")

Further US Patent Grant for Sareum's Kinase Inhibitors

Sareum (AIM: SAR),the specialist cancer drug discovery business, is pleased to announce that the U.S. Patent and Trademark Office has issued notification that a further patent has been granted for one of Sareum's key drug discovery inventions.

This patent*, which relates to compounds that inhibit or modulate the activity of kinase enzymes, forms the basis of Sareum's SKIL® drug discovery platform. The granting of this patent means that Sareum has extended its approved patent protection in the US for key elements of its SKIL platform and many of its drug discovery programmes. The Company has received similar protection in Japan and China and expects to receive it in Europe and other major markets in due course.

SKIL (Sareum Kinase Inhibitor Library) is Sareum's drug discovery technology platform that has so far produced the Company's Aurora+FLT3, Aurora+ALK VEGFR-3, FLT3 & TYK2 kinase cancer and auto-immune disease research programmes. SKIL can also generate drug research programmes against other kinase targets.

* Patent No. US 8,921,544

Sareum's CSO, Dr John Reader, commented: "This further grant of patent coverage for Sareum in the USA continues the strengthening of our patent portfolio, and enhances our negotiating position with potential licensing and collaboration partners".

Notes for editors:

About Sareum Holdings plc

Sareum is a drug discovery and development company delivering targeted small molecule therapeutics, focusing on cancer and autoimmune disease, for licensing to pharmaceutical and biotechnology companies at the pre-clinical or early clinical trials stage.

Sareum operates an outsourced research model, working with collaborators (SRI International, the CRT Pioneer Fund and Hebei Medical University Biomedical Engineering Center) and a world-wide network of research providers. Its research pipeline includes two programmes undergoing pre-clinical IND-enabling studies.

SKIL® (Sareum Kinase Inhibitor Library) is Sareum's drug discovery technology platform that has so far produced the Company's Aurora+FLT3, Aurora+ALK, VEGFR-3, FLT3 & TYK2 kinase cancer and auto-immune disease research programmes. SKIL® can also generate drug research programmes against other kinase targets.

Sareum Holdings plc is listed on the AIM market of the London Stock Exchange, trading under the symbol SAR. For further information, please visit www.sareum.co.uk