Rua Life Sci. Regulatory News (RUA)

1. London Stock Exchange ("the Exchange") has been monitoring the settlement situation in RUA Life Sciences PLC (ISIN: GB0033360586) following the Company's recent notification in relation to the issue of new shares which are conditional on shareholder consent. As a result of the deterioration in settlement performance, the trading of RUA Life Sciences PLC shares has been temporarily suspended under Rule 1510 of the Rules of the London Stock Exchange. Settlement of outstanding transactions can continue whilst the security is suspended. The Exchange will continue to monitor the settlement situation and when trading is to be restored, the market will be notified by Stock Exchange Notice.

2. Rule 5000 (Obligation to settle) and its associated guidance places an obligation on member firms to ensure that every on Exchange trade is duly settled on the agreed settlement date. This obligation remains even if the reason for non-settlement is a customer or counterparty having failed to settle other transactions in the same security.

3. Any queries on this Notice should be addressed to Market Supervision, Market Regulation, telephone +44 (0)20 7797 3666 (STX 33666) option 2.

Liam Smith

Head of Market Supervision

This Stock Exchange Notice will be available on the website at https://www.londonstockexchange.com/resources/london-stock-exchange-notices

Calls to the London Stock Exchange plc may be recorded to enable the London Stock Exchange to carry out its regulatory responsibilities.