Genedrive Regulatory News (GDR)

For immediate release 

23 October 2009

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Epistem Holdings Plc

2. Reason for the notification  

An acquisition or disposal of voting rights

Yes

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to the notification obligation:

Gartmore Investment Limited

4. Full name of shareholder(s) (if different from 3.):

250,000 shares - HSBC Global Custody Nominee UK LTD

200,000 shares - Nortrust Nominees Limited

50,000 shares - Gartmore Growth Opportunities

5. Date of the transaction and date on which the threshold is crossed or reached:

12 October 2009

6. Date on which issuer notified:

22 October 2009

7. Threshold(s) that is/are crossed or reached:

5%, 6%

8. Notified details:

A: Voting rights attached to shares

Class/type of shares

if possible using the ISIN CODE

Situation previous to the Triggering transaction

Resulting situation after the triggering transaction

Number of Shares

Number of Voting Rights

Number of shares Direct

Number of voting rights

% of voting rights

Direct

Indirect

Direct

Indirect

GB00B1VKB244

N/A

N/A

500,000

500,000

6.93%

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument 

Expiration date

Exercise/ Conversion Period/ Date

Number of voting rights that may be acquired if the instrument is exercised/ converted 

% of voting rights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments 

Resulting situation after the triggering transaction

Type of financial instrument

Exercise price

Expiration date

Number of voting rights instrument refers to

% of voting rights 

Total (A+B+C)

Number of voting rights

% of voting rights

500,000

6.93%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:

N/A

Proxy Voting:

10. Name of the proxy holder:

N/A

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder will cease to hold voting rights:

N/A

13. Additional information:

N/A

14. Contact name:

Restrictions and Disclosures Unit

15. Contact telephone number:

+44 (0) 20 7782 2324

16. Contact at Epistem

Matthew Walls

+44 (0) 7887 501 998