Covid 19 Mutations (one for the science experts)28 Apr 2020 23:02
Taken off a completely unrelated website (housepricecrash FYI), so I hope the poster doesnt mind me re-posting this, but this is of interest to us I think:
"On 16/04/2020 at 19:37, interestrateripoff said:
https://www.biorxiv.org/content/10.1101/2020.04.09.034942v1.full.pdf
Not a peer reviewed paper but:
Monitoring the mutation dynamics of SARS-CoV-2 is critical for the development of effective approaches to contain the 21 pathogen. By analyzing 106 SARS-CoV-2 and 39 SARS genome sequences, we provided direct genetic evidence that 22 SARS-CoV-2 has a much lower mutation rate than SARS. Minimum Evolution phylogeny analysis revealed the putative original status of SARS-CoV-2 and the early-stage spread history. The discrepant phylogenies for the spike protein and it receptor binding domain proved a previously reported structural rearrangement prior to the emergence of SARS-CoV-2. Despite that, we found the spike glycoprotein of SARS-CoV-2 is particularly more conserved, we identified a mutation that leads to weaker receptor binding capability, which concerns a SARS-CoV-2 sample collected on 27th January 2020 from India.
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This represents the first report of a significant SARS-CoV-2 mutant, and raises the alarm that the ongoing vaccine Development may become futile in future epidemic if more mutations were identified."
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Not sure of the efficacy/legitimacy of the research or researchers themselves but I think it has been hinted here (iananco?) that the longer this goes on the more mutations are going to occur...and much further down the line too i.e. years? Hence Scancells approach may be key in the fight against Covid19?
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