ASCO renal cancer trial result31 May 2026 09:14
Dr. Larkin concluded his presentation of the RAMPART trial as follows:
Durvalumab monotherapy following resection of renal cell carcinoma (RCC) showed no statistically significant improvement in Disease Free Survival (DFS) compared with active monitoring.
Durvalumab plus tremelimumab significantly improved DFS compared with active monitoring.
Safety findings were consistent with the known profiles of these agents, but rare immune-mediated adverse events, including fatal myocarditis and myasthenia gravis, were observed.
No evidence of a difference in overall health and quality of life (OHQL) was observed at month 15 with either durvalumab monotherapy or durvalumab plus tremelimumab.
….So there is still unmet need for treatment and hopefully MODI results will fill the gap 🤞🤞