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Wall to wall tripe....what a way to wake up to Easter weekend.

Firstly....two technologies - pre|CISION® and the linker/warhead of which AVA6000 is the first of dozens. Which one isn't working?

Secondly.....Last December the board sanctioned an extraordinary interview with a surgeon/oncologist who's actually using AVA6000 and he told us "it works".

Remember: "It is like having a rocket with a nuclear bomb inside, and the rocket is directed right away to the cancer cells – not to the body, because it would destroy the body, but to the cancer cells – and therefore able to spare the other parts of the body. Avacta has an incredible technology,".

Thirdly..... BP don't want to pay what Avacta asked for. Especially with the sunk costs of ADC v PDC

Excellent news for you Viking. Something for you to do for the rest of your life.....tilting at windmills. Look it up.

From 7th March RNS:

"continues to be observed when compared with conventional dose doxorubicin, including no observed events of severe cardiac toxicity, which are associated with conventional doxorubicin."

Imbecile. 11 patients surviving without damage to their hearts.

An accountant will want to see cash for at least twelve months (May 26) to sign off as "going concern". Cash to the end of this year (Dec 25) isn't good enough.

Is an Avacta licensing deal getting adversely affected by the loose cannons in Washington? The Sunday Telegraph thinks Big Pharma now has to cope with a new world of uncertainty and I do wonder if this is impacting Simon Bennett's efforts. The ST link is a pay wall and it's a long article so I'll not copy & paste except for the last couple of paragraphs:

"Big pharma, on the other hand, is fearful that tariffs will damage investment across research and development, which is crucial to future growth.

Senior drug leaders are privately alarmed at the direction of travel, yet few want to put their heads above the parapet.

David Ricks, the chief executive of obesity drugmaker Eli Lilly, flew the closest to criticism this month, when he said spending less on research would be “a disappointing outcome”.

It was a rare intervention from someone who struck a more conciliatory tone months earlier.

“My experience, having done this for eight years, is that there’s often more common ground than you’d think,” Ricks said, days after meeting Trump at Mar-a-Lago last December.

Now, it appears that the common ground was, at best, shaky.

A seismic shock is coming for the sector – all pharmaceutical executives can do is brace.

https://www.telegraph.co.uk/business/2025/04/13/trump-punish-drug-giants-world-will-pay-price/

I do wish it would roll back into its tomb.

Thousands of bio-tech companies around the planet - all working on next-generation compounds. How many are making a profit?

Easter Monday.

CLN payment news this week......cash or shares? If it's cash we'll hear sooner rather than later and they'll drag it out if it's shares.

Can't help thinking that AACR in three weeks might be pivotal. Three presentations by a tiny bio-tech? It seems a lot to me....perhaps not.

"Smart strategic move that could extend runway and boost sentiment quickly. 👍"

And would then provide the cash and legitimacy required to join NASDAQ.

Good Lord!....I agree with Wyn!

BV....If the leadership of an august body allows tampon dispensers in a male bathroom, for example, or males to compete against females in field sports, or Greta Thunberg and the eco-doomsters (Global Boiling anyone?) getting promoted as atmospheric scientists....then they shouldn't be surprised when the general public show deep scepticism with that leadership and begin listening to charlatans.

And this on both sides of the Atlantic.

BV......When the entire medical establishment refused to support females in their battle against overt male sexuality they also rejected their reputation for intellectual neutrality. Actions and re-actions, and consequences.

Shame about the patients.

Firstly they contract cancer then get suckered into using that Wetherby snake oil.

Calm down. You'll injure yourself.

Thompi......I've included the approximately ninety earmarked for Phase 1B. Probably at least 50 patients from this group will now have been exposed to pre|CISION®

D-Geeman....thank you. It is a good story but Zhou Enlai got the wrong revolution. Some years ago I corrected a very pro EU Reuters journalist who'd written that the American revolutionaries were, of course, influenced by the French Revolution. Wrong. It was the other way around. The US revolution was 1776....storming of the Bastille was 1789.

The Scientific Advisory Board runs this show and they would have pulled the plug on pre|CISION® if it hadn't worked perfectly in roughly 150 cancer patients. That's the Holy Grail BP spent billions on and decades looking for.

Avacta want a lot of money for it.

D-Geeman.....it was Zhou Enlai....the foreign minister.

B2HS2L....correct. It's the whole point of a Data Room.

Not long now. I did laugh at the village idiot suggesting eighteen months.