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Thread below courtesy of larry over on twitter!
Thermofisher know the importance of tracking all variants!
Some US states have sent zero sequences to international databases. This is a stark contrast to the surveillance effort in the United Kingdom, where up to 10% of all positive test samples also get sequenced, resulting in robust data about the genetic composition of the viral population. It is not a coincidence that B.1.1.7, the highly contagious variant strain now sweeping through the developed world https://www.thermofisher.com/blog/ask-a-scientist/genetic-surveillance-of-sars-cov-2-variants-a-call-to-action/
Sound like any company you know?
A diversified product portfolio of real-time and digital PCR, along with constant innovations by the companies leading to new product launches , are prominent factors responsible for the dominance of the companies. Moreover, a strong emphasis on partnerships and acquisition strategies in the market is likely to help attract high polymerase chain reaction market revenue in the forthcoming years. Https://www.fortunebusinessinsights.com/amp/polymerase-chain-reaction-pcr-market-102528?__twitter_impression=true
Polymerase Chain Reaction Market to Rise at a CAGR of 8.3% and Hit USD 8.14 Billion by 2026; Advent of Miniature PCR Devices Will Bode Well for Market
https://www.globenewswire.com/news-release/2021/03/03/2186019/0/en/Polymerase-Chain-Reaction-Market-to-Rise-at-a-CAGR-of-8-3-and-Hit-USD-8-14-Billion-by-2026-Advent-of-Miniature-PCR-Devices-Will-Bode-Well-for-Market-reports-Fortune-Business-Insigh.html
Seem to me that All future tests used must be able to check for variants!
Change made:
Under ‘Minimum standards that apply, added that for day 2 tests, the following additional data must also be reported: whether a variant of concern has been identified and whether a variant under investigation has been identified.
Day 2 and day 8 testing for international arrivals: minimum standards for providers https://www.gov.uk/guidance/testing-on-day-2-and-day-8-for-international-arrivals?utm_medium=email&utm_campaign=govuk-notifications&utm_source=67ba1168-a83f-4c5e-96dd-1838ea26c97a&utm_content=immediately
Weekly PCR and LFD testing of all staff
• Additional mid-weekly LFD test in between PCR tests.
• In tier 4, if there is a positive case in the care home from either staff or residents with PCR or LFD, all staff should test daily for 7 days.
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/949665/Care_Home_Testing_Guidance_visual_v291220-1.pdf
Any one agree with the above as i never know where to post or where to start looking on here any more?, was much better with one general thread tather than loads of separate threads, makes me use the site much less, anyone find the same?
I mean post below is important but didnt know where on here to post it!!!, confusing!!!
Govt assesment of molecular tests!
https://www.gov.uk/government/publications/covid-19-phe-laboratory-assessments-of-molecular-tests?utm_medium=email&utm_campaign=govuk-notifications&utm_source=f30942a0-e0ad-4753-b942-f65bf57294e9&utm_content=immediately
Testing increased at IGI Airport to help detect new Covid-19 variant
The testing process has suddenly increased about 10-fold; earlier about 500-700 international passengers were being tested per day, the lab is now staring at 7,000 plus numbers.
It was identified that between 3 am to 5 am, there will be roughly 1,200 passengers an hour who will undergo mandatory RT-PCR testing.
Testing increased at IGI Airport to help detect new Covid-19 variant https://www.hindustantimes.com/india-news/testing-increased-at-igi-airport-to-help-detect-new-covid-19-variant-101613978962677.html
Govt news Just released!
https://www.gov.uk/guidance/testing-on-day-2-and-day-8-for-international-arrivals
Guidance
Testing on day 2 and day 8 for international arrivals
Minimum standards for test providers.
Published 14 February 2021
British company racing to contain Ebola!
repeat prescription?
https://www.southampton.ac.uk/news/2014/10/10-british-company-racing-to-contain-ebola.page
https://mia.mk/four-die-in-new-ebola-outbreak-in-guinea-health-official-says/?lang=en
Looks like NCYT have a much improved LFT test on the way!??
Https://mobile.twitter.com/AWshares/status/1360922540810661888
At this time the best available assay for detecting the presence of C19 is PCR and Novacyt has a lead on this technology. They are developing an LFT to detect viral antibodies which again is the appropriate technology for that assay there being no equivalent to PCR for detection of specific antibodies. LFT to detect viral antigen is the wrong test due to lack of specificity and sensitivity. Novacyt are on the money
https://www.prnewswire.com/news-releases/worldwide-polymerase-chain-reaction-pcr-for-point-of-care-diagnostics-industry-to-2025---by-equipment-kits-and-region-301227547.html
No mention of NOVACYT but all our main conpetition are mentioned!
Respiratory infections such as influenza and respiratory syncytial virus are common targets for point-of-care diagnostics as these tests replace existing lateral flow immunoassays due to improved precision in results
Must be NCYT specific PCR tests being used judging by this article!
Https://www.dailymail.co.uk/news/article-9210159/Door-door-testing-South-African-variant-start-Surrey.html?ito=email-22815478&utm_source=overlay_newsletter&utm_medium=email&utm_campaign=cc_newsflash&utm_content=all
Experts fear there could be hundreds more cases already in the UK because PHE only analyses one in 10 random positive samples and the strain cannot be spotted in standard PCR tests. All of the swabs confirmed to have Covid will be sent to labs for further testing
This is not a good development!??
doctors in Brazil have identified two people who were infected simultaneously with two different mutated coronavirus strains
https://bgr.com/2021/02/01/coronavirus-infection-dual-strains-mutation/#
Very worrying!!!!
PCR testing certainly is though!!!!!
https://www.woking.gov.uk/coronavirus-information/coronavirus-testing-and-data
Https://africacdc.org/download/new-sars-cov-2-variants-in-africa/
Primerdesign is one of only two recommended african suppliers to keep track of the evolving strains!
info courtesy of a twitter post by Nolfa The anticipated consequences of the new SARS-CoV-2 variants on available diagnostic tools:
Nucleic acid amplification tests (NAATs)
Mutations of the 501Y.V2 variants have been mapped in the spike protein (S-gene), including K417T, E484K, N501Y; however, unlike the 501Y, this variant does not contain the deletion at positions 69-70. NAAT assays designed to detect multiple targets are less susceptible to genetic variation than assays designed to target a single gene. Currently, there are no assays approved through the WHO Emergency Use Listing (EUL) procedure that targets only the S-gene. There are also two NAATs on the WHO EUL which include S-gene targets: Thermo Fisher TaqPath COVID-19 and Primerdesign genesig® Z-Path COVID-19 CE. As both assays have multiple gene targets, the overall test sensitivity should not be impacted, which is consistent with manufacturer claims. The WHO prequalification and post-market surveillance teams will continue to monitor the situation1,2. Irrespective of which NAAT assay is used to diagnose SARS-CoV-2, it is important to monitor target failure rates; this may be a signal that a new variant is present, or can be important to trigger other quality control measures. Available data have no detailed information
We have a nice deal going with Unicef i do believe!
The United Nations Children's Fund (UNICEF) has purchased 1.2 million COVID-19 PCR tests for Ukraine.
“We have received 1.2 million PCR tests for diagnosing COVID-19 from UNICEF, they are all made in the UK.
Ukraine receives 1.2 million PCR tests from UNICEF
ukrinform.net