Member Info for TRENCH123

Most improbable and would not be helpful. Honesty and commitment of BOD here has never in question. The new CEO must be given an opportunity to improve shareholder value. I would like to see him buy a tranche of shares in the company to demonstrate his commitment

Viera comment two days ago :-

'I’m small long in the hope we get a new Ceo as under new leadership I believe this will be a 5 bagger plus'

I cannot see Suzy staying at the helm as this equates to more of the same. I would seriously consider investing much more with Adam in charge. Be interesting to see how this unfolds

'I am sure there will be a significant increase ....'. Well that sounds good enough for me. Keep the faith

Over the last couple of years JM has been trying to promote more awareness of the company. There has been the publication of several scientific papers by or involving PYC employees and a video presentation by PYC Consultant Hitesh Mistry on Project Optimus, which apparently was well received within the industry

The fact that PYC Chief Scientific Officer is reviewing an article relating to dose optimization (Project Optimus) would indicate that he is very well respected for his knowledge in this area. This must be a positive for PYC

Interesting that two of the authors are employees of Certara which is one of the major US companies actively involved in promoting Project Optimus

https://www.certara.com/project-optimus/

Have not come across anyone who is blaming Laura for losing them money. Be a bit childish for them to do so anyway

People need always to invest based on their own judgement and not on those of others. AIM is a minefield and people fully know this when investing

Lot of positivity towards end. Good presentation IMHO

Dr Adam Hargreaves (major shareholder in Valirx) made some encouraging comments last August about Project Optimus when a member of the Valirx SAB

His reply when asked about 'What trends are you currently seeing in Biomedical Research' was :-

''In my particular domain of interest - dosing and scheduling of cancer drugs - the recent Project Optimus initiative from the FDA has increased interest in model-informed decision tools and services. Project Optimus aims to create a paradigm shift for dose optimisation and selection from the Maximum Tolerated Dose (MTD) towards the finding of the Biological Effective Dose (BED) using modelling and simulation.”

Jim Millen referred to Project Optimus as Physiomics 'sweet spot'

I note that Adam Hargreaves is no longer showing as a member of the Valirx SAB I believe he only joined last August

Viera mentioned he had taken shares at 6p in the very recent placing

Are you doubting his respected judgement when suggesting further falls are guaranteed ?

For EUDA to make a big announcement about a potential merger and then just say nothing on the basis that investors will just assume its not happening would be bizarre in my opinion. I still expect a definitive announcement to be made

Timing of client contract signing is outside control of PYC. Proposal is sent out and then PYC must wait until decision approved by client. Always been the way here, hence you get rushes of news flow then nothing. Not a question of blame, just the way these type of businesses work

To keep things in context, the share price is up 65% compared with 6 months ago and the new CEO should be in a position to hit the ground running, so not all doom and gloom. Plenty to look forward to IMHO

Jim did mention that Peter was starting to take on some of his responsibilities at the last presentation so I am not particularly surprised by today's announcement

I have always found Jim to be a trustworthy person who has always given 100% commitment to developing PYC. I am sure that he must be disappointed at not advancing the business further under his leadership, particularly as regards the share price, but hopefully Peter can prove himself to be a very capable successor as CEO

I think there are grounds for Valirx shareholders to have some optimism

Stella has recently taken £20k in shares (small change for her I know) in the days immediately before resigning. Would she do this if she thought that Valirx share price was going to take a dive. I don't somehow think so. She must know the probabilities of success on VAL 201 etc as well as anyone and has made a calculated decision

I suffered losses during the George and Satu days and will not be jumping in, just interested to observe how this plays out

0.1% shares traded and 9.00% shift in share price. Meaningless movements until we get some substantive news and volume

Price will be up and down a few percentage points until we get a decent RNS release. Patience is needed and should be rewarded in my opinion

My thoughts exactly as yours on your comment 'Further PYC stay away from VAL the better'

A PYC tweet issued last week included 'We can’t wait to share with you all the exciting developments we have planned for the year ahead'. Interestingly, Valirx issued a similarly worded tweet including 'we're looking forward to showing you what we have planned for an exciting year ahead'

Probably coincidence or perhaps they use the same script writer. Could it be there is some form of closer working relationship between the two planned ?

Newuncle is spot on with his assessment - happens all across AIM now

One of most positive tweets I have seen from PYC issued last week. I am looking for some good near-term news flow to back this up. Contract news would seem well overdue