Member Info for TorquayFan

Hi. Everyone is interested LLass and I'm sure they'll donate if they can.

"University of Nottingham researchers are applying their expertise in a number of critical research areas; finding the best vaccine to combat COVID-19, discovering vital new treatments and protect the world against future outbreaks that could save many thousands of lives. Our leading researchers are using their extensive virology knowledge to help develop a safe and effective vaccine to prevent COVID-19. Led by Professor Lindy Durrant, in collaboration with colleagues and partners Scancell, work is underway to adapt an existing cancer vaccine platform for use against COVID-19. This DNA vaccine has potential to provide a vital effective and durable immune response to COVID-19. The vaccine has potential to also protect against new strains of coronavirus that may arise in the future. Alongside work on the vaccine, experts at our Centre for Research on Global Virus Infections are also involved in developing novel treatments for COVID-19, as well as assessing the risk for future pandemic events. They have already identified new coronaviruses in rodents. We now need to investigate their potential to jump species and establish new outbreaks in humans. Your support will go directly to our essential research efforts – finding the best vaccine to combat COVID-19, discovering vital new treatments and protecting the world against future outbreaks."

Professor Jonathan Ball, Director, Centre for Research on Global Virus Infections - "We bring together virologists across veterinary and human virology. The University of Nottingham has a leading vet school and a leading medical school – this rare combination allows us to fully understand the dynamic interplay between animal and humans that allows deadly spillover events like the coronavirus outbreak to occur. Working with active clinicians means our ideas and inventions can be rapidly progressed to help prevent and treat current and future virus outbreaks."

https://www.nottingham.ac.uk/research/covid-19/covid-19-emergency-appeal/covid-19-emergency-appeal.aspx

Yes well said Mr Glencross. Keep up the good work LLass.

Thanks for sharing that John Glencross tweet. Excellent. Let's hope Scancell's case gets through somehow or other!

Thanks for those clips Inan. Amazing stuff indeed. Looks like - 'Star Wars - the cell fights back" ?

Lots here. Can't see a Scancell mention ?

BioNTech (BNTX) Investor Presentation - Slideshow - https://seekingalpha.com/article/4348808-biontech-bntx-investor-presentation-slideshow?utm_medium=email&utm_source=seeking_alpha&mail_subject=bntx-biontech-bntx-investor-presentation-slideshow&utm_campaign=rta-stock-article&utm_content=link-2

I'm convinced that Scancell are in discussions here and there but there might be some way to go - we won't know - until she comes 'round the mountain when she does. Who sang that ? Aye aye ippy ippy aye.

No need to apologise M8. Good post. Oxford - reminds me of Oxford Utd and the dirty Atkinson Brothers kicking anything that moved (Graham and Ron). Big diggers they were, just like Inan LOL. Never liked Oxford LOL. Come on Scancell !

Not to confuse 'action' with 'progress' it seems to me that the 'Oxford' vaccine may be further along but it's path may not be the path to 'success' ? See this DM splash for the likes of me ! Any comment ?

I do wonder how BioNTech are doing with their 4 projects and wish them well - maybe they should talk to Prof. Lindy instead . . . .

"The coronavirus vaccine being developed by scientists at Oxford University may not prevent people from becoming infected with the disease after all, experts have warned. In the latest animal trials of the vaccine carried out on rhesus macaques, all six of the participating monkeys went on to catch the coronavirus. Dr William Haseltine, a former Harvard Medical School professor, revealed the monkeys who received the vaccine had the same amount of virus in their noses as the three non-vaccinated monkeys in the trial. This suggests the treatment, which has already received in the region of £90million in government investment, may not halt the spread of the deadly disease."

https://www.dailymail.co.uk/sciencetech/article-8331709/Oxford-coronavirus-vaccine-does-not-stop-infection-experts-warn.html

"The findings implied to the world and the public is that the effectiveness of mask-wearing against the coronavirus pandemic is huge," leading microbiologist Dr Yuen Kwok-yung, from Hong Kong University, said on Sunday. Dr Yuen, who helped discover the SARS virus in 2003, said the study was the first of its kind. He said that his team conducted the study because - while he has long supported wearing masks - world leaders, including the World Health Organisation (WHO), had questioned their effectiveness. https://uk.news.yahoo.com/coronavirus-wearing-surgical-masks-reduce-covid-19-spread-140800142.html?

The obvious conclusion is sometimes the right one - common sense as BJ says.

Kashdog - Botski ain't 'ramping' maybe. Just chatting with the BB. That's OK.

Bunsie NOT Ichor anyway - Inan explained that backalong. CSO has said Aug / Jan depending on finance coming. The idea of hundreds of thousands of Ichor devices appearing was a non starter anyway IMO.

I like that 'para' so let's have it again, more this time . . . "We can also reveal that a leading pharmaceutical company has already agreed to manufacture the vaccine which is being developed at Nottingham University, if it is ruled safe. There are high hopes it will be licensed because the scientists behind it have already used the same technology to develop an effective skin cancer jab."

Ivy it's logical to assume, as you say, that the approach must be validated by the "leading pharmaceutical company" which "has already agreed to manufacture the vaccine". Good thinking !

(Meantime fair to observe the 'coordinated media response' is still alive and well done CH/LD - maybe they have taken Ray P's advice on impact communication).

Let's hope we get an update tomorrow. ATB

Before my time Ruck . .

CC and Tenzing - thanks.

The third quoted sentence begins . . . "We can also reveal that a leading pharmaceutical company has already agreed to manufacture the vaccine".

More fantastic news Inan ?

UV rays, vit D and heat are all helpful as observed here . . . https://www.dailymail.co.uk/news/article-8325855/Has-warm-spring-suppressed-UKs-outbreak-Coronavirus-fell-sunniest-April-record.html However, in close contact, on rainy days and on buses/trains/indoors etc., only the 'D' can help ?

The pic in this link makes me shudder - 5 Policemen and a hooligan - months into CV-19 - NO masks at all. https://www.dailymail.co.uk/news/article-8326161/Police-arrest-activists-anti-lockdown-protesters-gather-Hyde-Park.html Wearing a mask - creates self awareness re. the crisis and gives some protection.
https://arxiv.org/pdf/2004.13553.pdf
https://rs-delve.github.io/reports/2020/05/04/face-masks-for-the-general-public.html
https://www1.icsi.berkeley.edu/~dekai/mirror/masksim/

Try again with this link. FT re. DT. GLA

https://www.ft.com/content/97dc7de6-940b-11ea-abcd-371e24b679ed?segmentId=cfda0fea-5138-496e-152f-177a0d0a61f5

Inan - isn't that either 'acclaimedly literate' or 'acclaimedly illiterate' as the case may be ? (Molten was Ruck's typo).

Now keep yourself out of mischief and have a long read https://www.ft.com/content/97dc7de6-940b-11ea-abcd-371e24b679ed?

Inan - hopefully, 'disease' not that ? ATB

'The findings could also help researchers create better vaccines' . . . 'The results have other significant implications for vaccine design'. Prof. Lindy has already arrived there has she not ? Someone should tell Ms. Rasmussen and Ms. Graham to keep up ! (I could be off my 'science' rocker here but). GLA

CC thanks for that link - I imagine Inan would approve ! I picked out 2 passages for interest :-

" “This is encouraging data,” says virologist Angela Rasmussen of Columbia University. Although the studies don’t clarify whether people who clear a SARS-CoV-2 infection can ward off the virus in the future, both identified strong T cell responses to it, which “bodes well for the development of long-term protective immunity,” Rasmussen says. The findings could also help researchers create better vaccines" . . . .

. . . . "To spark production of antibodies, vaccines against the virus need to stimulate helper T cells, Crotty notes. “It is encouraging that we are seeing good helper T cell responses against SARS-CoV-2 in COVID-19 cases,” he says. The results have other significant implications for vaccine design, says molecular virologist Rachel Graham of the University of North Carolina, Chapel Hill. Most vaccines under development aim to elicit an immune response against spike, but the La Jolla group’s study determined that T cells reacted to several viral proteins, suggesting vaccines that sic the immune system on these proteins as well could be more effective."

https://www.sciencemag.org/news/2020/05/t-cells-found-covid-19-patients-bode-well-long-term-immunity