RE: Biopsy14 May 2022 13:39
From a value to the share holder I'd say the secondary objectives are the most important::
• To characterise the pharmacokinetics (PK) in plasma, urine and tumour of AVA6000, of the preCISION and of active metabolites (doxorubicin and leaving group, ) when given as monotherapy, after a single dose and after multiple dosing. doxorubicinol
• To evaluate the initial antitumour activity of AVA6000 according to RECIST.1.1 criteria (overall response rate [ORR], duration of response [ DoR ], disease control rate [DCR] progression free survival [PFS ] and overall survival