RE: 200mg AVA 600014 Sep 2022 12:52
Inclusion criteria
3. Histological or cytological confirmation of locally advanced (unresectable) and/or metastatic pancreatic, CRC, NSCLC, SCCHN, ovarian, breast, soft tissue sarcoma and bladder cancer, who have either relapsed or progressed on SoC treatment or are intolerant or nonamenable to SoC treatment.
As a lay man that sounds to me that they are well down the route of treatment
But as exclusions there is:
Received a prior total cumulative dose of >350mg