RE: Anti viral taskforce28 May 2021 02:44
My thinking is the amazing USP this drug has is that it encourages our own immune system to wake up when it is dozing or compromised. It has specific advantages with Covid but unlike anti-virals has been shown to be effective even after 7-10 days of disease progression. Not only this but as far as I understand the 'in vitro' studies published there is persuasive science that it would work as a 'near term' prophylactic. We should understand however that it will not be used for this purpose except in exceptional circumstances for the next few years, probably until nuanced targeting is available and further trials have completed.
However, and I think this is the very mature elephant in the room, it will work against influenza which has been the major reason our hospitals have been so full during most winters over many years. It may be a relatively expensive treatment but not as expensive as building another 50 hospitals and training and employing thousands more doctors, nurses and ancillary hospital workers.
Once this life saving product is being widely used for Covid patients with breathing difficulties and has had a chance to show efficacy on a wide scale I expect the pressure for expansion of use in the NHS and elsewhere for flu patients will be huge. In some countries, maybe not the UK, it will be used on symptomatic patients even before they have had positive test results for Covid and this could increase the pressure for wider use even before formal P3 trials.
We do need the help of one or more international pharmas to reach full potential for Synairgen 1 but this could still be by means of regional J/Vs rather than takeover and like others I am sure discussions are ongoing.
As you can tell I am becoming increasingly bullish that our treatment can indeed save lives hopefully in 2021 but certainly for many years in the future. The whole thrust of medicine in the future will be to encourage, catalyse and optimise all elements of the natural human immune system. This will include diet, exercise, clean water and air and interventions in the form of exogenous interferons and other messengers which prove to be vital in the innate immune system. This is a better route to good health than targeting the adaptive immune system since the innate immune system, as its name implies is non-specific or 'agnostic' to the life threat.
You can see I am increasingly bullish despite the fact that on the investment front I could have bought all my shares now and not had the excitement and anguish of the last fourteen months.
Best of luck to all Synairgen supporters.
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