Roundtable Discussion; The Future of Mineral Sands. Watch the video here.
Lol! Good to see you're getting your excuses in early NFTs.
Gone from something will definitely happen in July, to 'oh its an invoicing thing' to now maybe something else means it won't happen like I was so confident about.
Could Inhaled Therapies be the Future for Fibrosing Lung Conditions?
https://www.breathingmatters.co.uk/about/could-inhaled-therapies-be-the-future-for-fibrosing-lung-conditions/
Chill the beans Mulder, obviously nothing for you to worry your pretty little head about then is there.
Poster who said NXP004 couldn't possibly be based on Lynparza / Olaparib and that no auditor would go near the company, seems to think he's got something worth saying.
Wouldn’t surprise me if he fully sold off nxp001 in the short term. The milestones would be some way off in the future, so may be worth the cash in the short term to get 002 over the line.
Lucky Dan ;-)
I understand Fx, but at the time of the deal he wasn’t involved with NFX so I don’t see why he would have done us any favours. You don’t expect a footballer to not score against a former team.
At the end of the day it was Brindley who signed off the deal, she didn’t have to do so. My interpretation is that she saw nxp001 as not of any significance so just wanted rid.
Corry, people seem to be forgetting that an insti just took out warrants for 4.5% of the company.
They wouldn’t have done so if they thought the company was going to dilute them within a couple of months.
They know the cash runway.
Dan wasn’t with NfX when that was finalised, it was Anne and Alastairs deal. Dans subsequent selling of his consultancy to Oxilio was solely related to oxl001 and not NFX side.
Hear you FX, but Oxilio was a straight full-on outlicense.
Collaboration would keep an element of NFX input into the next steps and process.
Theres plenty of ways to skin a cat.
"My preference would be that we would find some collaborative development partner and that a lot of the sort of knowledge that sits within the business, the network that it has in terms of NXP002 can go forward and be a part of building value and some retained value in progressing that asset value chain so that would be my preferred path."
As a reminder below is a link to a list of ongoing mid and late stage IPF trials (as of February 2023)
https://info.evaluate.com/rs/607-YGS-364/images/IPF%20article%20Feb%202023.pdf
The interesting thing about this is how few of these are inhaled and then how many have failed recently. This help open up the market for other options with a greater bank of data behind them.
From the phase 3 list we know that the following have failed.
Roche - PRM 151
Fibrogen - Pamrevlumab
So this leaves only two IPF treatments in phase 3.
In the phase 2 the following have failed/difficulties.
Pliant - Bexotegrast - reported as being taken to phase 2b but showing lesser efficacy than in earlier tests.
Algernon Pharma - NP-120 - Phase 2b for IPF 'postponed' with no further date, only being tested for chronic cough now.
Bristol Myers - BMS-986278 - Phase 2 halted after three participants developed cholecystitis, an inflammation of the gallbladder. Also showing indications of liver inflammation
Calm down dear… you’re getting quite worked up for something you aren’t invested in.
That’s good then as the company won’t be paying for phase 1.
Correction, the £465k figure was the start of the period not the end.
So March was £260k, meaning approx £390k before outgoings.
See... its not hard to admit when you make a mistake.
Anyway, at end of March the cash position was £465k
Since then they have received £70k from placing and circa £60k from Lanstead to date.
So approx £595k in cash prior to outgoings.
They can claim cash payment of 33% of R&D costs from the government. Which would be circa £150k cash.
Plus they have a further £85k due when warrants are exercised.
Chill the beans.
Someone’s grumpy today, must be missing out on todays strikes.
Lol!
The fact that someone thinks this is invoiced is laughable.
Sometimes it’s better just to admit when you are wrong.
*sighs* Those at the back need to pay attention.
“The First Subscription proceeds of £330,000 will be pledged to Lanstead under a Sharing … …. monthly settlements (subject to adjustment upwards or downwards) to the Company over four months, as detailed below.”
“Admission and dealings in the First Subscription Shares and the First Value Payment Shares is expected to commence at 8.00am on 17 December 2021.”
“The monthly settlement amounts for the First Sharing Agreement are structured to commence approximately three months following Admission of the First Subscription Shares.”
“The second Sharing Agreement (the "Second Sharing Agreement") provides that the Company, in return for pledging the £1,320,000 proceeds from the Second Subscription Shares, will receive 16 equal monthly settlement amounts as measured against the Benchmark Price. The monthly settlement amounts for the Second Sharing Agreement are structured to commence one month following the receipt of the final settlement due under the First Sharing Agreement.”
So 4 payments to commence 3 months after first tranche are admitted.
1st tranche admitted to market 17th December. 2021
First payment Mid March 2022
Second tranche commences July 2022 for 16 months.
Second tranche ends October 2023.
As the saying goes....
Those who can do, those who can't teach.
For those who have trouble reading.
“ In December 2021 the Company entered into a Sharing Agreement with Lanstead, split into two tranches of new shares issued with payments to be received over a 20-month period from March 2022 to October 2023.”