RE: SVNS a BANGER 💥💥7 Jun 2025 15:40
Some snippets from Proactive interview
"The results of the phase two for that program were groundbreaking," Tennyson said, highlighting that participants improved from 2% sobriety to 86% six months post-treatment.
The phase Ill trial is being conducted in partnership with the UK Department of Health at an unusually low cost of £800,000, a figure Tennyson noted is "unheard of really, in the biopharmaceutical industry."
The trial is being carried out within the NHS and supported by UK addiction specialists and the Department of Health and Social Care, adding national relevance to the program.
That program is in phase three, which, for your audience to understand, is the final stage in clinical research before being able, subject to being successful, to apply for approval to market your drug. The results of the phase two for that program were groundbreaking, Stephen. And this is really important — people coming onto that trial were sober 2% of the time. So they were sober seven days a year.
Those that went through the active arm of the trial achieved, on average, 86% sobriety in the six months post-treatment. So to move from 2% sobriety to 86% sobriety in the six months post-treatment is really unheard of in the treatment of this debilitating disease of alcohol addiction.
That trial is now in phase three, and it's been executed through a partnership now between Solvonis and the UK Department of Health.
Through that partnership, the trial is actually being executed at a very, very low cost. The cost to Solvonis is only £800,000 sterling for a phase three, potentially to finish a trial, is unheard of really in the biopharmaceutical industry. What's really important for us is that the trial is being executed in the NHS in the UK. So all in all, for Solvonis, which is a UK-incorporated, London-listed biotech, it's really important for us having that UK-relevant phase three trial for alcohol use disorder being executed in the NHS, with many of the addiction key opinion leaders in England active in the trial, being supported by the UK Department of Health and Social Care. So we're really pleased to have that asset now within Solvonis. And we're very excited about the potential for that program.