Member Info for Saxondale

Further to the 4th submission cycle of results submitted by Faron on 10th March on Clinicaltrials.gov
Now showing that submission is now cancelled as of 16th March ( yesterday )

Again , I can't dig in any further to understand what that might mean , other than what it says .
Cogs clicking away in the background , and things moving fast .
Just need a juicy update now.

The big Immunology conference in Canada is cancelled -
Not sure about 2 investor events in Finland this week in Turku and next week in Helsinki . Websites still show them as active .

oh that 11am one was an uncrossed trade
anyway its 2.62 to buy at the moment

Its showing on Vox Markets - 17600 @ 2.51 at 12.00 , plus a 11641 @ 2.51 at 11.00am

Bit of news about EMA ( European medicines Agency )
European Medicines Agency (EMA) is taking action to accelerate the development and availability of medicinal products for the treatment and prevention of the new coronavirus.
The statement said the EMA is “ready to support medicine developers with all available regulatory tools to advance and expedite the development of effective measures to fight and prevent the spread of this virus”.

This was posted 7th Feb 2020

More news soon I'd expect

Us Govt prepared to do whatever it takes .
Shouldn't take them long to read the list of medicines available for ARDS and in particular ones that FDA have just signed off on for a global late phase III.
Whilst not wanting to steal Zens job , I do feel we are on the countdown to boom time .

Mary , I just can't beleive that Faron are not already in talks with Govt bodies , whether European or American .
The EU gave Faron a 6 million euro grant in 2012 to help development.
Both of our established manufacturers are German ( although Rentshler has a US manf plant - should we ever use them )
The US are actively seeking to push through development drugs to help ( they have an agency called BARDA that is soliciting for pharmaceutical companies that they can help speed up development )
Both my gold shares dipped today ( 10% )
Faron has stayed steady , and I can't buy more than £1k without negotiated order .
Good luck to all LTH's

Further to my spotting of an update in the ClinicalTrials.gov results section - we have a new date entry.

There is a new date of March 10 2020 - Results submitted to clinicaltrials.gov

So Faron have submitted back some results back to them again, the day after they announce FDA protocol acceptance.
I don't know what the reasons for this are - but we are now in the 4th submission cycle of sending internal results back .
In the first two cycles it took one or two months for Faron to address any issues and return results.
This time it took 6 days .

I'd be a rich man if I knew that .
As mentioned we have big shareholders adding to their pot , at well over the latest placing price £1.90 .
We've had chunky buyers taking stock well into the £3's
Only 58% of stock is in free float , that's only 25 million shares.
If it dips below £2.25 I will have another chunk , but considering we were high £3's before the market crash , on the hope of an imminent RNS concerning Traumakine funding and manufacturing , and we still haven't had that , then we shouldn't even be down here .
Add in an unbelievable global situation , with the main cause of death being ARDS ,the very same condition we have a drug for ,entering late phase trials.
Add in a cancer drug that without the current situation , would be getting a lot more attention.
Add in a new drug of AOC3 inhibitors that they are working on ( another drug similar to Traumakine that reduces inflammation and vascular damage )

A lot of progress made since that £1.90 placing - hence us bouncing up to £4 just on sentiment .

Who knows what the market will throw at us next week , people may sell , but the big shareholders know what this company is worth long term , the CEO owns 7% of the company , and they've been working on this for a long time .

Made in 2019 but gives more info to the ARDS issue and how CD73 ( Traumakine) works.
For those new to Faron and learning about what it is

https://www.youtube.com/watch?time_continue=102&v=P2mm-J_DxLI&feature=emb_logo

Is Timo related to Victor Kiam ? ( you may need to be of a certain age to relate to that )

I'm keeping a count too of how many different ways we can spell Traumakine .
I've got about 3 . I started with Traumaline , had a few Tarumakines and even a Traukamine .
Hopefully in a year or so it will be so well known it will be included in spellcheckers .

The Traumakine page had been updated as of yesterday
Now has a Coronavirus mention plus a video link to show how Covid 19 causes ARDS and how that causes death.

https://www.youtube.com/watch?v=okg7uq_HrhQ&feature=youtu.be

Often mentioned on other boards , but are we a takeover target ?

Three main attractions apparently for takeovers are :
De-risked assets in the form of recently approved drugs, or nearly approved drugs , tick
Product pipelines of more drug candidates on the way , tick
Shares trading well-below their 52 week highs , tick

Either way - putting Clevegen to one side for a moment , I can't see how the Traumakine development is not going to be exponentially important .
Hopefully not long to wait to find out

The timing of the WHO to avoid steroid use with ARDS patients is also a godsend .
Hopefully hospitals are following guidance , so that every severe ARDS case recently diagnosed could be eligable as as Faron candidate .
It took months for the recruitment to be filled for INTEREST
Surely it will take hours this time

I don't think we'll have to wait long to find out how the Traumakine story is going to play out .
For the first time since this Covid-19 started , tonight's news are showing people parked up in ICU treatment . Some on their backs, some on their fronts , ventilators etc . 196 dead in Italy just today.
WHO World pandemic . Govts worldwide getting nervous.
Not a huge list of candidates of drugs that can offer some hope of combating ARDS . Certainly not ones that have already proven safety in phase 3 trials , and have years of data that show efficacy .
Like Markku said - The data is the data , you cannot take that way .
Orphan Status for ARDS
Lets see what the next update RNS tells us .

Mayfly , just read all your posts from 2017 .
A sober dose of reality, fair play to someone who bought in before the SP crash .
All your points are valid .
I'm one of the lucky ones who bought in post crash , and have only seen rises and a success story .
Thankfully , the BOD and big investors have all held together through the hard times , and we have a second chance at success .
The Covid-19 , horrible as it is , may provide us with an opportunity to get Traumakine proven , and launched successfully and profitably .
The Clevegen program looks more promising on every update . Still nothings guaranteed , but good news is better than bad news . and good news bolsters the SP .
Will we reach £25 ? Lord knows , stranger things have happened . I just hope I don't look like Gandalf by the time we get there .

They can diddle about with the price as much as they want .
Can't see there being much shortage of demand for our ARDS drug when it finally hits the shelves .
1 week , 1 month or 6 months.
They've had best part of a decade getting Traumakine to this point .
The whole team must be working like crazy behind the scenes.

certainly some big trades today .
hard to see which are buys and sells
I'd wager that 59.56k @ £2.97 was a buy , as all of a sudden it was £2.81-2.85 to sell .

I was reading back in 2017 when INTEREST trial planned , Faron had noted that they planned to extend the use of the drug beyond the patients recruited for the trial , on a compassionate basis . It would be available to qualifying named patients in the EU , and they had plans to offer the same in the US .
Not saying that Faron need any PR , but I'm still staggered that when we are on the cusp ( not in a good way ) of a major breakdown in hospitals abilities to cope with patients with ARDS , that more people haven't picked up on what we have .
Goalposts and rules are changed daily/hourly .
Busy times ahead

They just offered me £3 for all my shares , sitting tight , if you can stay level on a day like this - good times ahead

Fins seem happy enough - 5% up there