RE: Progress of the Modi 1 Trial30 Jan 2023 22:44
This is the actual RNS statement...
"Based on the safety data analysed from Cohort 2, post-period the ModiFY trial was expanded at this dose for Modi-1 monotherapy in three tumour types. To date, 13 ovarian, two breast and three head and neck patients, including one in Cohort 3 in combination with a CPI, have been dosed with no safety issues. Modi-1 stimulates CD4 T cells which may directly impact tumour growth. However, in some patients these T cells may need to be protected by CPIs if the tumour environment is highly immunosuppressive."