Vagus, I am only selling in the morning if we have an RNS spike, but it will only be a few, ready to buy back when they lower the SP some 45 minutes later! The question is depending on the RNS how big will the spike be? Imagine if they open tomorrow morning with a RNS stating the share will be suspended for 48 hours! Sure on Wednesday we will have the new employee shares on the total share register. Let’s hope all the Avacta employees do very in deed!
Yorkshirepragma, you are totally correct, many great companies have been ruined by market manipulation and shorting. You have to say, although very wrong in his way, Mr Elon Musk certainly dealt with those trying to short Tesla in a very robust manner. He has certainly made sure his investors have been well rewarded. I am sure that Alastair Smith has the same ambitions for Avacta share holders. Don’t think we will get to $1500 per share, but over time £20 per share with success in multiple projects as well as the pre|CISION chemotherapy projects will certainly nail that ambition. The current BAMS and POC Covid19 testing solutions are just the opening opportunity for the business to makes its global name heard.
I just wonder, could we get updates on both those projects this week? How cool would an ‘RNS a day to keep the shorters away!’
Just as a pointer, if people want to buy shares in the worlds largest companies at a reduced risk, just buy into Fundsmith Fund, or for Tesla fans try the SMT trust fund - SMT.L.
Easy way to gain some of the worlds biggest companies into your portfolio. Many pension funds have these as staples in their portfolio.
No advice given!
Avacta is my strong buy!
One thing I really do hope after the big mouth of AIM - the fool TW has said it is a good time “to short Avacta,” that we get the most monumental RNS in the morning and shoot up to £2 plus, to put another nail in the coffin of his shorting ideas! Anyone agree?
The total number of cases in the US was 66,528 in one day. A new record! Even the UK has recorded 650 new cases.
If anyone thinks the market for testing is going away, they are very wrong indeed.
Chengdo4, I was looking today for exactly this information. The media have gone quiet on new cases and number of deaths. People are complacent and the world is thinking, ‘it’s not going to effect me!’ Well whilst we ‘carry on living‘ the virus is going to ‘carry on spreading!‘ We all know how quickly this grew in the first place. This time there will be no mass lockdowns. This time it is testing which may help.
Makes you think.
Avacta is a Biotech company with two operating segments, the Therapeutics operations based at Avacta’s Cambridge site (pre|CISION™ ) and the Diagnostics operations ( Affimer® ) in Wetherby.
Avacta has two key areas - Affimer® technology a uniquely developed technology which is used as a diagnostic to find virus’s based on a human protein called Stefin A. The Affimer® platform is Avacta’s proprietary therapeutic platform with its intellectual property covered by several patent families.
Affimer® technology projects with LG Chem just on licensing can be worth up to $310 million.
ADC project backed by Astra Zeneca for PBD Warheads - loaded affirmer drugs $500 million.
A joint venture in South Korea with Daewoong a leading Korean pharma company, to develop the next generation of cell and gene therapies, incorporating Affimer proteins to enhance the immune-modulatory effects. Avacta holds 45% of the business but the finance is provided by venture capitalists where the market potential is still too large to actually pinpoint as there are NDA's in place so the market information can't be shared. Huge potential!
The huge project with Affimer® technology with Moderna which again will give drug deliveries for mRNA delivery is still progressing. Huge potential!
Affimer® technology to detect Covid19 using Antigen tests the partners are Cytiva (LFD) and Adeptrix (BOMS) with distribution through 4 Mass Spectrometer suppliers (both close to production)
There are existing 5 other Affirmer evaluations progressing, 17 other projects already delivered for evaluation, and a further 7 development projects initiated!
Avacta’s pre|CISION™ technology can be utilised in a drug conjugate linker or to generate chemotherapy pro-drugs that are only activated in the tumour.
When added to a chemotoxin, the pre|CISION™ substrate prevents the chemotoxin from entering cells and therefore renders it inert until the substrate is cleaved in the tumour microenvironment. Using this pro-drug approach, the systemic exposure to the chemotoxin is dramatically reduced, and the safety and therapeutic window of these powerful anti-cancer treatments are improved.
pre|CISION™ partnerships which are looking to start with opportunities in AST, Breast and Ovarian cancer the EU/ US market potential is around $1.5 billion.
Research Opportunities for the reader:
Broker Note: https://mcusercontent.com/d9ebd7c1aa0f3dbc5fab42eca/files/28b0a706-057a-4dda-bc5f-e24c2afca3cd/AvactaGroupplc_24_6_20_FINAL_BG.01.pdf
The last Presentation:
https://youtu.be/DzoxXCB4or0 - from 1hr 33min 50 seconds
Latest from Avacta: https://avacta.com/how-diagnostic-test-performance-is-measured/
A good read from a well-known researcher is found here:
Investment for 2020, it sure looks good!
Good evening everyone,
I have had a quick check in a few times over the last couple of days. So very good discussions taking place. I have been very opportunistic with some more buys as the price has dropped. I keep thinking why are most investors so impatient. Everyone reads what Warren Buffet says with respect to building and holding and having researched wait for the market to catch up. We have had chapter one, the seeds are sown and the most important work with respect to the two Covid19 testing is in place. The news about production partnerships must be close, the news that the assays are being transferred are close, the news relating to a partnership to produce a neutraliser for the virus is close. Q4 should see the start of one of the most important cancer chemotherapy stage 1 trials commencing. The accumulation of the projects are sure to bring great reward. The virus continues to reach higher and higher numbers across the globe and the final impact is nowhere near reached. The UK investors have gone a little cool, because they see the UK going back to a new ‘normal level’, but the world is far from that.
The world markets have been performing way ahead of the reality, but reality is about to set in. UK news about job losses and a complete reset is coming, and the last 4 months has changed the way we all do things. This will have a huge effect on the market, until life can be reset again. The fight to ensure mass testing, a treatment that can be relied on and even more important cancer patients get chemotherapy treatments without side effects resulting in multiple hospital treatments due to super low immune systems and neutropenia which are the oncologists and patience worse case situation is critical.
Avacta, have multiple solutions ready to be taken to the next level. We are so close. Rewards come to the patient.
When the impatient sell, the smart money continues to buy. That remains my position here.
Will we get any news tomorrow, we all hope so, but next week must be the start of some really good news flow.
Too late? I don’t think so!
Have a good evening.
Good evening all,
Well the awaited news is taking the time in needs, the market markers have lowered the price, scared a few maybe into selling, but just to make the most I have added another £7k today. No sells (although I wished I had sold a few on opening).
We don't know when the next RNS will come, but we know there are many due and all will have a significant impact.
Some may be getting twitchy here, but look at the global situation. When everyone goes out in August for the subsidised meals out and cheap days out the risk will increase here as it will across the world. The government have to do something to boost the economy! But what will happen with the virus. Our test will make a huge help in keeping places open where possible.
There is still no doubt in my position here and I have continued to build it and will do more as I see fit.
I am not all in and will never go all in, in any share. I think we will see a trend upwards of the days ahead.
Global2017, far from me or anyone advise you with your investment plan. But given that the share price normally spikes on an RNS waiting for the share price to drop before selling makes you sound a little foolish. Normally people invest low and sell higher. Not high and then sell low. If you have too much money and you need to give it away there are many charities in great need at this time.
I would suggest you create an upper limit to sell each morning just in case there is an RNS at around 10% above the SP at the close of the previous day and at least you should make some money out of the situation.
I sometimes read comments on the board and I fear for peoples wellbeing!
I hope you are well?
So the new employee shares are on this date. Clearly if news comes before this date the company will continue to share items as required. But the really big news may well come after this date.
In the meantime we may continue in a pattern which the shrewd can continue to build there portfolio ready for big news items.
We can be sure that a big news item could come at anytime, but most likely in a 7am RNS. So being out over night and missing a sharp rise would be highly risky.
This virus is showing no signs of retreat, in fact the opposite and countries and taking risks with there people because the economies need to move on. Collateral damage is inevitable, but the human race will continue on. Testing and the right PPE is vital.
The World Health Organization has acknowledged there is emerging evidence that the coronavirus can be spread by tiny particles suspended in the air.
The airborne transmission could not be ruled out in crowded, closed or poorly ventilated settings, an official said.
If the evidence is confirmed, it may affect guidelines for indoor spaces.
An open letter from more than 200 scientists had accused the WHO of underestimating the possibility of airborne transmission.
The WHO has so far said that the virus is transmitted through droplets when people cough or sneeze.
"We wanted them to acknowledge the evidence," Jose Jimenez, a chemist at the University of Colorado who signed the paper, told the Reuters news agency.
"This is definitely not an attack on the WHO. It's a scientific debate, but we felt we needed to go public because they were refusing to hear the evidence after many conversations with them," he said.
So many are still no wearing face coverings when out or in the work place! The need for testing grows everyday!
Good morning all, the news will come when they are ready, the key point is that the share price is recovering nicely in anticipation and that is what is needed.
Let's see where the mm's take us today and if people will continu to build there postions. We know this is very likely to grow quickly with the right news based on the pipeline presented by the company.
Hope you all have a good day.
We often use the words ramping a share. But, seldom do you see shares jump quite so much. Tesla the ‘small’ electric car company today has had their share price jump by a mere $163 today and they have a market cap exceeding 254 billion US dollars. Good news for those with SMT shares. That trust fund me listed in the UK is Tesla’s largest share holder.
I am sure our Jonesrichard must me a Tesla supporter. So there share price is $1371 per share. How high will it go? Mr Elon Musk will be heading to be the worlds richest man.
Interesting off topic.
O&W I have a client who is distributing a RPOC test which involves a pin prick of blood. Results in 15 minutes. The test is manufactured in the US. It is sold in minimum boxes of 250 tests in a box at £10 per test. Due to NDA I am not going to tell you who this is or it’s specifics. But, for all it is a very good guide of where we need to be. But, I will say I am very confident that our test is going to be more accurate. But that company has been a world leader in malaria testing. Which is an area that Avacta could easily look at.
I have said many times sales price is key. I think our price will start higher but will fall over time as production is ramped up. If the product is so good it will sell under its own merits.
I have many Global clients making medical devices and supply them.
I didn’t know Dianne Abbott was in the UK government Alwayswinning? Why would the UK government order 100 million units. I guess you know the UK population numbers.
Given what MrsKOB mentioned this evening I stick to social distancing! They will be better spending the money on our virus neutraliser. Hopefully only need 1% of the volume of the vaccine. Much more cost effective.