Member Info for ratcliffewriter

'The Placing was significantly oversubscribed.' Nice to see.

And now 7-7.50. Maybe the American involvement and the comprehensive update with funding to support, plus the possibility of an avidimab deal have removed some of the underlying questions. After all, I think a placing had been discussed and accepted a while ago. Now it is done it is big enough to be useful even without further non-dilutive funding, and of course gives a better negotiating position.

6.80-7.50 Seems like the placing is being well received.

I notice that redmile have investments in BioNtech among others. Interesting to have got American involvement now.

Good to see that Bumsie has managed to account for his off-board interaction with you. Please remember in future that all intercourse must be approved in advance by a representative from the dark side. This isn't an intrusion into your privacy, it is purely to ensure that nobody strays from the doomie script, and as you know unauthorised intercourse comes with a heavy penalty and if it all goes wrong can cause a pain in the bumsie. But they know all about that over there. It's not called 'the dark side' for nothing ...

Tell you what Bumsie, I hope they aren't paying him in anything other than washers because they sure as hell aren't getting any value (apart from comedy of course)

It's great to see traditional activities being revived - heavy horses for ploughing, micro breweries for real ale, boutique gin distilling, and of course ravings about a 'secret club' of share manipulators. This does not include any reference to any twitter group emanating from the 'dark side', that's to be ignored of course, but the 'secret shareholders' club is a delightful blast form the past, and makes a refreshing change from the eternal round of board/science/financing criticism topped off with a bit of '4p on the horizon' which has really been getting very stale lately. Usual hillside at midnight lads? Don't forget, clothing optional.

A pleasant looking start to today, and good to see that Admin have removed the more abusive comments in the wake of our lovely rise.

Steady now knowallsi, otherwise they'll realise you are my stockbroker. How else would you know what I'm invested in?

Alas you may be correct there. No doubt after dusk here he will stalk the corridors (if not the pupils) and deliver the usual roundup on whinges pleased the BOARD of Governors and who HAS not. I may have to put some blotting paper down my trousers to lessen the pain of the cane, as he punishes my little Bumsie.

Long may we hear of your successes.

I know it has just ticked up to 6-6.50, but could willy waver or whatever he's called please keep it down, Ivy needs to concentrate to earn his ten grand a day.

So you must the honourary president of the Glee Club. Care to name the other members?

Keep 'it' up sock boy.

I don't know whether C7 would fit the label of 'Glee Club' member, but he posted last night that it 'could be an interesting week' and so far today it hasn't disappointed, unless of course you are a player to the ADVFN gallery. Speaking of which, Ivy hasn't yet had the decency to illuminate this board as to which posters he would categorise as 'Glee Club' members. Might be useful if he did, but I'm not holding my breath. Perhaps he doth protest too much which is apparently a sign of an inferiority complex....

Perhaps he will have the guts to post here and explain what he means, instead of playing to the pond life for shallow adulation.

I should have added that your name did not spring to mind while I was writing that post!

Scancell have had a habit of updating with news, and until news we have to wait, but we know they don't rest on their laurels during any silence. So given there is a global pandemic it is reasonable to assume any combo trial progress is slowed but not abandoned. The addition of trial centres doesn't require an rns so in true style doesn't get one, but the information is in the public domain and has been found where it should be. What I was trying to get across is that far from stagnating as a company, exciting and potentially profound work is carrying on, but it is easily buried on a board by a movement of voices denying it by persistent distraction work. Those recent rnss have as a result imo been sidelined whereas with a better sense of proportion should be headlined.

Interesting to hear the rather conspicuous complaints from certain quarters about ‘lack of news’, so I looked over the RNSs, and it doesn’t take much effort to find news –the latest two are well worth rereading, if you have perhaps been conditioned to read them too superficially, or too used to what is actually significant scientific advancement. But the pace of this does seem to be increasing lately.
The RNS of 24th June announces the resolution of problems which now allow the drug to go to manufacture for clinical supplies in Q3 of this year (that’s now). This means the final hurdle has been removed from the way of manufacturing ‘a completely new class of potent and selective immunotherapy agents’ which has provided astounding results in preclinical trials.
Look at the other news from that RNS – a peer review of Modi-1 in the Journal for ImmunoTherapy of Cancer, so not a speculative write up, but reviewed by others who are happy to put their names to the review. The title says ‘induces potent CD4-mediated anti-tumor responses’. Not ‘may’ or ‘could’– DOES. The RNS also reminds us of the scope of Moditope –a clinical trial in patients with solid tumours including triple negative breast cancer, ovarian cancer, renal cancer and head and neck cancer. And these are hard to treat cancers don’t forget.
Then the RNS from 12th June– Guess what?Another peer reviewed document, concerning the function of Avidimab. In crude terms a bolt-on turbocharger to an antibody's potential therapeutic properties. Peer reviewed, not speculation, and in a journal of the AACR, so top level territory.
Further back in the RNSs was the announcement of the Covidity platform on 24th April – I appreciate this was not quite a whole 3 months ago which is a long time for those goldfish for whom a fortnight’s trading is a lifetime, but it was a very quick response to an urgent global problem. Of course it isn’t an optimistic shot in the dark, it is as the RNS explains built on the proven safety and ‘well beyond the established norms’ results of SCIB1, with the aim of producing a simple, safe, cost-effective and scalable vaccine. A realistic aspiration on the overall scale of things? I would say so.
So a new platform based on proven safe science three months ago, five weeks ago a peer reviewed publication of another platform (which has first of three interested parties nearing the end of a one year evaluation period), and a peer reviewed article about the massive potential of MODI-1 just over three weeks ago.
It is plainly wrong and disingenious that those who claim not to be updated have been so vociferous while what is actually significant and validated fact has been produced by the company in (literally) recent weeks. It has been said before when these sort of campaigns get waged on the BB, but those who expect a weekly newsletter to help their trading really need to pull their socks up. Or sock anyway.

Chewing raw garlic would give you a clear 2 metre distance from anyone else. Except in France maybe.