Member Info for Patagucci

So do we still think SPRINTER failed its primary end points due to patients on steroids... wouldn't there have been a cohort of patients not taking steroids to compare to?
And also, why did SPRINTER not originally only have people in most need of Tx in their selection criteria? Finding out after the drug failed that it works best on <65yrs and people with respiratory problems I thought was something we all universally knew

Anyway, hoping this is the first of a few good RNS's, ACTIV2 data next, then trial or JV I hope.

So we it works best on people who are in need of it most. (A fire to put out)
It works with little side effects.
On those it did work for, it did so with a reduction to severe disease and death by 70%

Game on?

Agree. Time for Synairgen to regain investor confidence and show the world what it’s aiming to do.

Why would there be an RNS?
Well its my understanding they are releasing deep dive data which could have an impact on SP, therefore this has to be RNS's prior.

All I would say, I’ve tried reading the signs with SNG in the past, and been stung badly. On paper I think this looks promising, not long to wait now. Also attending this conference isn’t the first time for synairgen. I look forward to seeing if this time will be more successful.

For #media #investors: We will be presenting at @ATScommunity from 13-18 of May taking place in San Francisco, California.

We look forward to seeing everyone there!

Read more: bit.ly/3FxTKcm

#SNG #ATS2022

I have my fingers crossed this event is where the tide will turn for Synairgen. The need hasn’t gone away for a broad spectrum antiviral, and it never will. I will be listening closely. I’m expecting an RNS either tomorrow, Friday or Monday morning. GLA.

I think people need to be realistic about this event.
It is going to disclose information which could affect the SP hence the embargo.
We are awaiting further info from sprinter, it is likely to be released in this presentation.
We are awaiting further info from ACTIV-2. There is no evidence that will be disclosed in this presentation but is likely to be released ‘soon’
A JV/TO or EUA won’t come immediately from this, don’t get your hopes up. But this will be a platform to present our case.
Deep dive data of Sprinter will really let us know what direction this company will head in. I’m hoping it’s good but I don’t expect the SP to move drastically on this alone.
Good luck all genuine investors.

Thanks everyone, answered it perfectly.

Interesting, I am no statistician so I’ve learnt something new. I guess now the questions are what is this sub group, and is this new p value enough to get this drug to market.

With the latest RNS showing the p value at 0.051, can someone explain to me why this is important… I thought it had to be less to or equal than 0.050 to be significant?

Thanks

Yes and what if we have a future respiratory virus which takes years to produce a vaccine (if ever). Having a drug which works then, with the safety profile of SNG, would come in very handy.

Did I say 'what if', probably 'when' would be more accurate.

Regarding long covid. Have we ever had any proof Synairgen works against long covid? People often seem to think there is a chance it will prove it does. But I sometimes wonder how people get to this conclusion.

16th/17th May presenting at conference data from Sprinter
25th May financial results.

Not long to wait then. Like so many here I’ve been badly burnt with SNG. But I still hold hope, like I said last night, covid isn’t going away, we are a mutation away from further deaths. The need for a broad spectrum antiviral is still as important as ever.
It will be interesting to see where synairgen ends up. My bet is T/O or JV.

Possibly so. The COVID pandemic isn’t going anywhere. We learn to live with it. But we will always be one mutation away from further deaths. Let alone the decreased potency of vaccines over time.

One things for sure, the need for SNG will always be there.

"The positives are we are presenting at a prestigious event in May and it’s hard to believe we’d be doing that unless the company had found interesting insights on the failure of Sprinter and hopefully significant findings."

Synairgen have presented this event before right?
I'm long on SNG, but feel although these events are important, until we get positive data, JV, EUA or any sort of commercialisation, this is all just background noise. Sorry if this makes me sound a little ignorant, I understand the importance of these events but just feel we need something more than going to an event for me to feel there is progress here.

Can you imagine if the sub group were non steroid taking participants…

May will be a big month for the company it seems, according to today’s RNS.

I don’t know but AIMdetective is someone I follow on twitter, generally their posts are good quality and I would trust.

Were results poor? I’m invested in 4D hence why I probably have this out look. But this drug has no side effects much like Synairgen, and on patients where nothing else would work, the drug gave a 25% increase in survival rates. Cancer treatments are extremely valuable, but a cancer treatment like this and the results it achieved deserves the increase today. Long term I still think £1.50 + is on the cards for 4D

I am a health care worker, after somehow managing to avoid COVID since the pandemic began, I now have COVID. Just a few days ago I went to my first concert in years. 10,000 people were there and surprise surprise I now have it.

To be honest, so far it’s a mild cold. But I do believe the UK, and maybe even the world seem to be acting like this pandemic is over. It isn’t. Many of my friends in and out of work also have it currently.

After THAT P3 result I was gutted, still am, I don’t expect to make my money back anytime soon, but the need for synairgen hasn’t gone and I really hope for the worlds sake, if synairgen really does what many of us believe it does, it gets made available to the masses very soon.

I know people say this will be seasonal, like flu. But it appears to be more like waves, with multiple waves a year. And we are just playing Russian roulette with how bad is the next variant going to be.