RE: News imminent12 Feb 2026 16:45
Pk....How it works small cohorts " usually 3 patients each patient receives a higher dose than the previous one, "A dose limited toxicities window "28 days to monitor safety ,,,,,If no DLTs this escalates to the next Dose...if DLTs symptoms are present then the escalation is Paused/modified....Early remission will not change the Dose Escalation ONLY SAFETY decides if the the next dose escalates ! when the C/T 1b/2 the phase 2 dose is chosen @ this point you will monitor positive clinical procedures are meanful,,,,,,Phase 2 more patients are enrolled & determines what the toxicity levels are across the cohorts/relapse rat/survival/event free/safety.....Approval🐭