Member Info for Noise

True. I am afraid I cannot back that up with a source.

Winnifrith referenced it at one point after the Valiseek investor funding night at the end of 2017. I think there was some debate over whether they would prefer a partnership or an IPO, assuming that either was palatable and on the table.

Either way, technically it probably doesn't matter that much for us, assuming you have shares in Valirx who currently have majority control in Valiseek. One would assume that any IPO would require Valirx to offload or dilute that majority control, but that's entirely in a technical domain I do not pretend to understand.

Rumours suggested a Valiseek IPO in Q3 2018, with phase 3 trial submission applied for at roughly the same time.

Google says 25p? If I knew what was driving it I might invest more.

I don't think they've officially announced the exact spending of that £75m. They posted the following at the time on a .gov.uk website. UCLH has a number of great trials going on, including VAL201, automated surgical robots up the whoopsie and HIFU (killing tumours with a focussed acoustic energy beam) for smaller tumours.

"The new studies will particularly target higher risk groups including black men – one in four of whom will develop the disease – as well as men aged 50 or over and men with a family history of prostate cancer.

Over 40,000 patients will be recruited for more than 60 studies in prostate cancer, to test treatments including more precise radiotherapy, high-intensity focused ultrasound, cryotherapy, alongside supportive interventions including exercise and dietary advice.

This new research drive comes as ‘one stop cancer shops’ are being piloted in ten areas to catch cancer early and speed up diagnosis, particularly for those suffering with less obvious symptoms."

https://www.utilitydive.com/news/pge-to-replace-3-gas-plants-with-worlds-biggest-battery-projects/526991/

Some seriously large battery projects:

PG&E) late last week requested approval from the California Public Utilities Commission (CPUC) for four energy storage projects totaling about 2,270 MWh

Queensland's SolarQ, which is planning to pair a 350 MW solar facility with a battery system of up to 4,000 MWh.

The VAL201 trial is still advertised as a going concern on the UCLH website, so one assumes it continues as planned. I also believe that trials typically report back every 3 months or so, perhaps explaining some of the news vacuum.

Haven't heard a dicky bird about the proposed multi-site trial extension, that was rumoured towards the backend of 2017,

Any particular reason for move today?

It's crazy reading through the Australia battery storage performance and costs. You can really see why lithium is taking off.

The battery plant installed operated 90% cheaper than the gas peaker plants/frequency stabilisation, but also did it far (FAR!) faster and more accurately.

Just reading the notes...gas peaker plants have problems now. When needed they had been charging around $12000 per MW of supply, while the Tesla battery packs charged around $270 per MW of supply. With activation times measured in miliseconds. Rumoured to pay for itself within 12 - 18 months...

Sooo, unusual process (non-spodumene) and local govt trying their best to reintroduce communism...

Doesn't bode well. Annoying because any mine like this based in Australia would be $1.5bn by now

Out of interest, what are the impurities like at Cinovec? Or lots of Tin and Tungsten vibrated out? What do they not like in batteries?

Primary bid type raisings are the future, all that is required is to imprison a few hundred brokers and their self interest.

3.1p hit...another 11.9p to come? ;) Probably not today. Maybe with something material on an RNS.... 6 months left to trial 8mg dosing...oh I cannot wait to see those results (if disappointing, of course, I will re-evaluate my holding!)

To the frightful bore who was warbling about communications. Perhaps you could explain to the group what you would have done differently? In the last year VAL have had PR, marketing, attended various cancer exhibitions, held investor nights, regular RNS progress updates, various director phone and video updates, several Hardman research updates. Typically updating every 3-4 weeks. But apparently, the communications guy doesn't communicate, because somebody on a message board is a bit ADHD and grumpy? God there are some strange types on the web.

Are apparently scoping out a site near Leipzig for their "bigger than the Tesla gigafactory" in Germany, $1bn battery plant, across the border from Cinovec.

From recollection George was discussing the very early trials of VAL201 in prostate cancer, how I interpreted it was essentially "seems to be safe, no side effects so far, indications of PSA reduction at very low dosing rates". I think that was possibly at 1-2mg dosing, while the theory indicated that the sweet spot would be 4-8mg/kg. So at that point one of the bigger points was probably the lack of side effects.

Yeah, on the positive side of things, it does appear that for the first time Valirx are going into market with a real live product and commercial pack for a phase 3. Taking into account various risks etc., it may be a good turning point, as if VAL401 does actually work then significant commercial progress will occur within 3-6 months, well within the investment timeframe of a typical AIM investor. £30m initial milestone (plausible? who knows) does work out at about 6p a share. Would be interesting to see if the partner would then progress phase 2 on several oncological conditions while simultaneously running the phase 3 on lung cancer (adenocarcinoma was it?). In theory HSD10 gene dysregulation could function on many cancers/adenocarcinomas in different parts of the body, as the core problem is that overexpressed HSD10 levels prevents cells from dying (resulting in an undesirable tumour growing). Reading the VAL401 patents, they describe various laboratory tests that apparently resulted in a significant reduction in growths in certain prostate cancer, lung, pancreatic, ovarian carcinoma, certain breast cancers etc. A serious amount of work, although arguably less effective than chemotherapy (considering chemotherapy is more or less the medical equivalent of drinking bleach and killing all cells, I'm not surprised at that), but risperidone has far more tolerable side effect schedule (you may not even notice it). Interesting times. I've never really known what to expect from 401, it remains a wild card, on paper I like certain elements of it, at other times I wonder if it's an elaborate pyramid scheme, but the Doctors involved appear to have genuine backgrounds and government support (to a certain degree). Suzy sounds too....nice to be a conwoman!!

I don't think there's anything set in stone about a July 2018 deal for 401. I believe it is simply that the scientific package would be complete by July 2018, permitting any potential partners to enter into a commercial discussion. Assuming interest anyway.

Well possibly. But we actually have a MoU with HE3DA and they kept saying they were going to use Czech lithium. So officially it's what we know about.

So EMH are currently making 200kg of raw lithium materials, HE3DA are slowly ramping up their 1.2GWh battery factory for late 2019, can we infer they are likely to be getting a significant quantity of that sample? The Czech trade office says the 1.2GWh HE3DA factory has plans in place for a rollout to 15GWh. 200kg is about 0.5MWh and not a bad starting point. 15GWh would be about 7.5kt, so around a third of the rumoured initial output of Cinovec supply. Obvs - I'm all in waiting for the 100kta Cinovec mine........ ;)

PS if VAL are actually in advanced talks regarding a cancer drug licensing, that is worth more than £3m, which is roughly what the market cap increase was this morning. Can we hear 5p anyone? ;)