Scancell founder says the company is ready to commercialise novel medicines to counteract cancer. Watch the video here.
FDA bingo administration question JHFH :)
If an rns of CH lifting comes at any other time tomorrow, not the usual 7am, does that still count as your call? Because - more seriously - when would the notification have to come to Hemo for it to be able to be in an 7am rns or would the FDA considerately inform Vlad before 7am?
As I said mid-afternoon, many thanks to those who've bothered to write interesting and informative posts today - that seems a while ago now. Surely an exciting week ahead: we can't all be right in JHFH's FDA bingo but anyone being right will do!
A very interesting, informative and clarifying day's postings on here today, thanks to all. Strange (and pleasing) to think we may be just ten/s of hours away from the rns which Vlad, Hemo and many wise lths here have been working towards for so long.
Sorry for so much posting this morning :{ I know CAR-T is a treatment but Is CBR potentially an antidote/cure/treatment or what exactly?
It does indeed Haywain, many thanks. Particularly with CBR in the background, it's going to be very interesting to see how long it is before CAR-T is attracting offers.
Bit confused about phase 1/2a. If/when Hemo goes clinical, are you suggesting Haywain, that the first trial could be a trial of 10-20 patients (phase 2?) and completed within a year? Or would that be after the successful trial of one patient? Sorry streaming cold-fog.
Happy to be revised HH especially as you let me keep the Microsoft dream :)
Much more seriously, if CBR were to fulfil its mind-boggling potential, have to be concerned about whether the human race is capable of enabling worthwile lives for all those who are saved.
Many thanks again, John - I hold with renewed confidence and interesting to see if Mr Nesis mentions penalties or negotiations on the 31st.
Thanks JHFH. So the strategy is most likely to be to get CAR-T into trials and then, guided by Prevail (experts in the field) to find the best buyer to licence the treatment to, in order to provide adequate funding to take CBR forward. And figures like ÂŁ50/60m seem to be achievable for this.
Then on to CBR which as far as I understand it, isn't a single treatment (like a Land Rover 90 chassis) but a multi-use platform (like Volvo's base shared across their whole range) upon which can be built the antidote/cure/treatment (?) for many viruses and even some cancers: incredible.
But if the licence for CAR-T which is a treatment solely for one relatively small set of patients, could be worth ÂŁ50/60m to Hemo, how could you possibly predict the value of EACH individual licence for EACH worldwide deadly virus potentially infecting millions of people? Microsoft indeed.
And we are shareholders in the company which might have such a life-changing impact on the world. We few, we happy few.
Hadn't thought there could even be more, Hulver! Hemo-fountain indeed then, with CAR-T the fundamental and vital pump-priming mechanism. That must be one set of very excited facilities :)
Thank you HH. Sorry if I was over-positive with that percentage, I tried looking through your past posts but don't know how to just see your Hemo posts.
Thanks too for the reality check on phase one duration: I wasn't thinking but of course it has to be that sort of time to see a treatment's effects on a living patient.
Thank you for the considered, informative response, John. As you've doubtless realised, I personally am looking at Poly as a long-term divi/income provider and even as this is delayed, the "higher group profits and falling debt" will presumably be reflected in eventual dividends as well as the sp. Do you feel then Poly's concern about the penalties is holding them back from attracting buyers or could it be that a sale is actually actively being sought at this time?
John - you said recently "Penalty will have to be paid, and me thinks it may be a too heavy a price to pay, which will leave POLY with no option but to stay put till the conflict ends." Tragically for the people and country of Ukraine, it is hard to see this resolving at all yet alone soon. Hoping this doesn't sound too trite and selfish but is there any way the dividends could be paid without the sale or end of the conflict and if not, do you think shareholders will start to drift away from Poly without them - and would Poly care if so..?
Some Saturday night wonderings as Hemo excitement bubbles :)
Taking it somewhat as read that Hemo is going clinical in the very/pretty/quite near future, I remember HH (I think) giving a very useful summary of the chances of getting through each clinical stage - over 80% of success at phase 1 as I recall. Has as anyone got thoughts on how long phase 1 trials generally take? Also wondering which is generally deemed to have the greater effect on the sp: going clinical in the first place or getting to phase 2 trials?
May all long-termers get the rewards their loyalty, faith and tenacity deserve!
And, scarcely here a year, all thanks for sharing your knowledge and helping to keep us newbies on the path to Hemo-glory
How come MyIPA gets 3 goes??? lol
Great update/summary by JHFH this morning - needs passing on all those people we know who deserve the Hemo-glow :)
Okay it wasn't this Thursday (at 7am anyway) but why not Thursday next week or the following - as indeed chosen by HH. Normal statistics for Hemo rnss can't be relevant for this new territory and maybe it is "rude" to submit an application to the FDA on a Thursday but I can't see Vlad taking offence at receiving approval on any day. Or indeed at ANY time on ANY day. All we do know - for certain - is that it's coming. And soon. GLA.
Appreciate what you’re saying about Tempest, Saint. It’s great to hear about that magical event but it’s also grounding to hear why it’s not so likely in Hemo’s case. And “just” JHFH’s 1000% at this time would be so so pleasing :)
Laughable.