For Mark22 May 2020 00:31
Yes it has been rejected twice Mark.
This is not the first time that Iclaprim has been rejected by the FDA.
In 2009, when Iclaprim was proposed for the treatment of complicated skin and skin structure infections (cSSSI), the FDA indicated that additional clinical data are required to demonstrate efficacy, and refused to approve it. Iclaprim was under the aegis of Arpida, a Swiss company, then. Motif Bio acquired the rights to Iclaprim from Arpida in 2015.