RE: Abstracts18 Mar 2026 09:07
"They also combined AVA6000 with an ATR inhibitor (BAY1895344). ATR is a protein that helps cancer cells repair DNA damage. Blocking it can make cells more vulnerable to DNA-damaging drugs like doxorubicin. In the liposarcoma model, adding this inhibitor made AVA6000 about twice as effective (the dose needed to stop growth dropped by half — a sign of synergy, where the combo works better than either alone)."