Member Info for kevkan

theboyg
They are not in a position to talk about Act 2 P2 until results are known not their trial. However assuming we graduate to Active P3 it will target hospitalised and hopefully breathless on a global platform which for me speaks volumes.

Nothing more to add

Part 2 of the trial, was designed to study the efficacy and safety of inhaled SNG001 in up to 120 COPD patients with a confirmed respiratory viral infection, commenced in October 2018, and recruitment into the trial commenced in earnest in January 2019.

In March 2019 the Data Safety Monitoring Committee (DSMC) completed its planned safety review of Part 2 of the trial. In its review, the DSMC did not identify any safety concerns for patients currently enrolled and it endorsed a pre-planned broadening of the patient population to allow patients with more severe COPD to participate in the trial.

Seaboy
What a remarkable piece of work to be given such an in depth look at what is actually going on in our hospitals, how you all manage to cope in such demanding conditions is extraordinary. The constant pressure lack of a suitable anti viral dealing with death is beyond reproach. I for one wish to thank you and your colleagues for all you do.

Kevin

Sorry if already posted but quite significant
Blaze at giant Tesla battery farm takes firefighters four days to put out

https://www.msn.com/en-gb/news/world/blaze-at-giant-tesla-battery-farm-takes-firefighters-four-days-to-put-out/ar-AAMRoJW?ocid=msedgdhp&pc=U531

Within a couple of hours, Reuters reported that Ruud Dobbers, an AstraZeneca executive vice president, had said the group was “exploring options” for the business.

While nothing has been decided, he told the newswire, that sort of talk on the record from a senior executive is usual a sure sign that change is coming.
https://www.msn.com/en-gb/news/other/astrazeneca-may-be-done-with-vaccines-that-s-sad-but-not-surprising/ar-AAMIDXT?ocid=msedgdhp&pc=U531

We need a progress update from the company now too many unknowns it's one thing being careful what you release but to release nothing is unfair to share holders. I am at a loss now with so called warp speed with so many hospitals enlisted how difficult can it be to administer a life saving treatment.

Never a truer word written
'Whoever hoped that the vaccines alone would solve the problem, they are not. What is necessary is a strategy that brings as many vaccines as possible on the one hand and, on the other, also understands the limits of the vaccine.'

https://www.msn.com/en-gb/health/medical/pfizer-s-vaccine-significantly-less-effective-against-delta-variant/ar-AAMf99u?ocid=msedgdhp&pc=U531

Hurtle
RE Ivermectin, have you seen this Huge study supporting ivermectin as Covid treatment withdrawn over ethical concerns
The preprint endorsing ivermectin as a coronavirus therapy has been widely cited, but independent researchers find glaring discrepancies in the data

https://www.theguardian.com/science/2021/jul/16/huge-study-supporting-ivermectin-as-covid-treatment-withdrawn-over-ethical-concerns

Six UK cases: Fast-spreading Lambda variant puzzles Covid scientists due to 'unusual set of mutations'
A Covid-19 variant called Lambda has left Scientist from the World Health Organisation puzzled due to its ‘unusual set of mutations’.

The Lambda strain, denoted as C.37, was first discovered in Peru and has spread to nearly 30 countries in the last four weeks, including Argentina and Chile, according to the Financial Times this weekend.

The variant is already in the UK as Public Health England has confirmed six cases, five of whom had travelled abroad, according to a Reuters report.

Unusual set of mutations
“One reason why it is hard to make sense of the threat from Lambda, using computational and lab data, is that it has rather an unusual set of mutations, compared with other variants,” the FT wrote, quoting Jeff Barrett, director of the Covid-19 Genomics Initiative at the Wellcome Sanger Institute in London.
“Lambda has a unique pattern of seven mutations in the spike protein that the virus uses to infect human cells. Researchers are particularly intrigued by one mutation called L452Q, which is similar to the L452R mutation believed to contribute to the high infectiousness of the Delta variant,” according to the report.

High transmission rate
Citing WHO data, the paper wrote that Lambda now accounts for 82 per cent of all new Covid-19 cases in Peru, which has the highest Coronavirus death rate in the world.

The govt say they are handing back responsibility to the people, I hope the people stay responsible

Not a hope in hell if ministers bend rules what chance is there the minions will support a voluntary code

Sanchez
Although it hurts one has to accept reality and I agree with most of what you say however I still believe this company could and should be a major powerhouse. I never have understood the secrecy and witholding of information demonstrated in the past having to rely on BBN et al to try understand where they are going and what they are doing is outrageous really. One can only hope they will learn and improve, sadly, I have lost confidence in them now which is a shame. I shall continue to maintain a small investment with a view to increase should the tide turn.

New health secretary Sajid Javid has warned the UK will have to learn to live with Covid as he said he was confident lockdown restrictions in England could be lifted on 19 July.

Gonna need a lot of treatments then we only had 22868 new infections reported this morning not a problem then

Head of Communications

About us: Synairgen is a respiratory-focused pharmaceutical company preparing to launch SNG001 for the treatment of COVID in the US, UK & EU.

Sacrilege when there is a known treatment that could be expedited

India has reported a record daily rise of 6,148 deaths from Covid-19 over the 24 hours ending Thursday morning, taking the overall death toll to 359,676.

It comes as the number of Covid deaths in the state of Bihar was revised by the health department on Wednesday. The department had earlier said that the number was under 5,500, but added 3,951 deaths to the overall count after verification.

More than 94,000 new coronavirus cases were reported in India in the past 24 hours, and its overall caseload now stands at 29.2 million.

https://www.msn.com/en-gb/news/world/coronavirus-news-live-indias-daily-deaths-soar-to-record-high-as-state-revises-tally/ar-AAKTeua?ocid=msedgdhp

COPD 1.6 million deaths from smoking alone
On the back burner atm but this is a far bigger problem than covid what price do you put on a treatment that can help relieve symptoms show a marked improvement.
There were nearly eight million deaths associated with smoking in 2019, and 89% of new smokers were addicted by the age of 25, global data suggests.
Researchers found that in 2019, smoking was associated with 1.7 million deaths from ischaemic heart disease and 1.6 million deaths from chronic obstructive pulmonary disease.

https://www.standard.co.uk/news/uk/washington-china-india-bangladesh-indonesia-b937681.html

From memory I believe they suggested they were also following up on the P2 hospital patients if correct that could be significant

I came to the conclusion some time ago that Fortune is a visionary/ entrepreneur he revels in deal making pulling out the white rabbits. Whilst that in itself is to be applauded it also takes determined steel to follow through. He came across as bored with the mundane business of reporting the results as he has on the last couple of occasions. However I will carry on and support albeit with a much reduced holding.

If this variant were to have a 40-50% transmission advantage nationally compared to
B.1.1.7, sensitivity analyses in the modelling of the roadmap in England (SAGE 88)
indicate that it is likely that progressing with step 3 alone (with no other local,
regional, or national changes to measures) would lead to a substantial resurgence of
hospitalisations (similar to, or larger than, previous peaks). Progressing with both
steps 3 and 4 at the earliest dates could lead to a much larger peak. Smaller
transmission advantage would lead to smaller peaks

https://www.gov.uk/government/publications/sage-89-minutes-coronavirus-covid-19-response-13-may-2021

scary

Oakleaf 72
As much as I would like to claim moving in celeb circles unfortunately it couldn't be further from the truth
I need to apologise to you and the board for my faux pas the recommendation was written by Mike Payne I simply copied it of the Richards Linkedin page.

Talk about fits the bill what a stonking catch
I worked with Richard, directly and indirectly, for several years at Gilead. As a leader in our Respiratory and Antiviral franchises in both the US and UK, Richard demonstrated true leadership in motivating cross-functional (inc corp dev, R&D, operational) teams to a successful outcome (portfolio growth/ laun..