RE: Reasons to be excited….theres loads!11 Dec 2025 06:57
World-first platform launch imminent — OptiMAL® (mammalian display of fully intact human IgG) launching next Monday at a global antibody conference (AET).
• Validation from the highest level — US National Cancer Institute pilot produced multiple antibody hits, including difficult peptide targets, with single-digit nM affinities.
• NCI want to keep using OptiMAL — RNS explicitly states NCI have asked to continue using the platform “for years to come.” In my view Nothing gets printed like that unless discussions are far advanced.
• Multiyear, multi-target deal being finalised — CEO confirmed at IMC that Fusion are “working through the details” of a multi-year agreement with NCI.
• Revenue acceleration already underway — Company guided H2 revenue to be ~80% up on H1, before any OptiMAL/OptiPhage revenue is counted.
• New high-margin revenue streams incoming — Kincaid: “Three whole new platforms… will open up additional revenue streams to what we do today.”
• Commercial pipeline already building — ~£1m in new business pipeline before Optimal platform has even launch.
• Hiring into growth — Fresh recruitment across Purification, Analytics, and senior commercial roles, including a new hire from a direct competitor in mammalian display → shows confidence and momentum.
• OptiPhage licence opportunity — Licence agreement already “in play” for OptiPhage work; could add another recurring revenue stream.
• AI/ML antibody discovery expansion — Active work with Oxford University’s Prof Charlotte Deane (UK authority in ML-antibody design) + Fusion’s own AI/ML-Ab libraries coming.
• “Step change” in fortunes — CEO at IMC: “I can only expect that this will start to close the valuation gap… we’re in a much, much better place.”
• Global pharma engagement — Company confirmed active discussions and deals with top-tier pharma for their services in RNS earlier this year.
• FMI Launchpad grant — £1m Directly supports their platform and asset development and significantly reduces cash burn.
• High-value tech compared to peers — Mammalian display on full IgG at scale is unique. Others (AbCellera, Distributed Bio) work at fragment or yeast/phage level; Fusion’s workflow delivers “fully human, developable antibodies from day one.”
• Lean, reset, stronger company — After the 2023 reset, FAB now has: lower burn, stronger tech stack, validated platforms, and the most compelling commercial story since IPO.
• Tight free float + insider alignment — Low liquidity + board/directors holding meaningful stakes → amplified upside on good news.
Obviously execution risks but they’ve managed the