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Very interesting.. Obviously they knew about this but couldn't say last week at the investor presentation

Didn't juhu say that they could take bex al the way themselves without a partner? Funding would be the deciding factor!

Hold onto your shares guys... They could be worth 25 or more in a shorter time than we even thought possible!

We are holding well considering the rest of the markets over the past month and today with putin invasion of the ukraine!

Mopedi

Thanks for this! 10x market cap with a US listing! Wow

Although the faron team speak english, I think they are limited in getting their message over at times. particually during the QandA yesterday.

However everything is looking good!

I think they answered 2 of my 3 questions
Partnerships(always in discussions, not yet, maybe do it all themse that answer could be also to send a message to a partner to pay more

date for market (cant say)

And never answered was is a US listing coming... maybe that's too sensitive to answer ATm

There will be an opportunity to ask questions... anyone listening in, are you prepared, anything that's been bothering us.. this could be the opportunity to get the answers

https://faron.videosync.fi/r-and-d-day/register
2pm uk time

If I remember correctly the question of results on of bex on 1st diagnosed cancer paitents rather than end of life was put to marku before and all he said was we can expect better results

Is that tool still stuck down the shaft that's apparently stoped them producing!?!

Was in these guys along time ago and sold at a loss during the waster Colin hutchingson days.

You would think they would capitalize on the gas now! Problanliy too much work for this lifestyle company

Welcome aboard sheerclass

Great news espesally on the identification Of biomarker that would tell them who bex works on. So for example the 40% of positive cases of breast cancer turns into 100% of those selected will have a positive outcome!

Also this: 'Hematologic malignancies'

This has been added, also had to Google. It!
'There are three main types of hematologic malignancies: leukemia, lymphoma and multiple myeloma'

So this will be added to a trial at some point.

"Dose Escalation Trial of Bexmarilimab (FP-1305) Plus Pembrolizumab"

Is this new or did I somehow miss this!?

Pembrolizumab aka Keytruda owned by Merck!
Very interesting.

Markku has spoke about bex being a stand alone and combination therapy. Would be interesting what conversations behind the scean AR at play between Merck and faron!

Sax, I think you deserve the whole bottle of wine... And may followed up with a whiskey night cap..

Bad day over on sng

Sax I know you had some skin in the game over there... Hopefully it will recover or we lift off and you make some of your losses back.

RNS 7am tomorrow... I'll try again

Ot invested here but if it's any consolation in 2018 faron pharmaceuticals who were in phase 3 trials for there drug Traumakine which was to treat ARDS failed even though phase 2 and 1 were excellent results.

The cause of the failure was using cortosteriods at the same time.

There is the issue here.

Average down and batten the hatches for a while and you may well be ok but it hurts for sure the pain today.

The drug no doubt works but they will need to redesign it without steroids

Wow
So their phase 2 trials went really well but phase 3 never worked.
Their RNS reads like ours from 2018

"87% of patients in this trial received systemic corticosteroids for COVID-19 at baseline whereas none did in the Phase 2 study of SNG001 in COVID-19[1]) may have compromised the potential of SNG001 to show a clinical benefit in respect of the primary endpoints for this study."

The drug probably works fine if taken without steroids.

Well we know this...

Here the issue. Corticosteroids messing with the results. Faron pharmaceuticals had the same issue back in 2018 with their infer on beta drug clevergen.

The drug probably works fine if taken without steriods

"87% of patients in this trial received systemic corticosteroids for COVID-19 at baseline whereas none did in the Phase 2 study of SNG001 in COVID-19[1]) may have compromised the potential of SNG001 to show a clinical benefit in respect of the primary endpoints for this study."

RNS tomorrow morning 7am! :)

So faron tweets out a article about bile duct cancer early this morning.
One of the main cohorts of the mantis trials.
Around 30%of paitents benefits from bex as mentioned on the last update

Wonder if they have a bigger breakthrough on this which will be RNSed or mentioned at the investor thingymigig

13:00:10 256.00 50,000 Unknown* 128.00k

"Dr. Fjällskog will share updated survival data from the ongoing MATINS trial and provide an overview of the accelerated bexmarilimab development plan, including a review of the latest biomarker analysis and strategy"