finnCap & Liberum brokers comments today22 Aug 2022 15:43
(Alliance News) - Analysts were upbeat after Open Orphan unveiled a "substantial" new GBP10.4 million contract which is expected to underpin revenue in 2023.
Shares in the London-based pharmaceutical services firm were up 5.7% to 11.89 pence each in London on Monday morning.
On Monday, Open Orphan said its subsidiary hVIVO has signed a GBP10.4 million contract with an "existing top five global pharmaceutical client". This is the third human challenge contract signed with the client, it added.
Mark Brewer, finnCap analyst, said "This is the fourth human influenza challenge (seventh challenge study) and third challenge virus manufacture that Open Orphan has signed in 2022, illustrating big pharma's recognition of the benefit of conducting challenge studies prior to larger, more expensive field trials."
Under the contract, clinical research company hVIVO is contracted to manufacture a new batch of H1N1 influenza challenge virus, leveraging off an existing in-house generated challenge model, and to conduct a human challenge trial to test the client's antiviral product.
Manufacturing activities will begin immediately and are expected to be complete by the second quarter of 2023.
Once completed, hVIVO will conduct a phase 2a double-blinded placebo-controlled human challenge study which is expected to be complete by the fourth quarter of 2023.
The majority of revenue from the contract is expected to be recognised during 2023, Open Orphan added.
Liberum analyst Edward Thomason estimated that around 70% of the revenue will be recognised during 2023.
Brewer said: "This contract underpins the growing order book of revenues 2023.
"We make no changes to our financial year 2022 forecasts or 44p target price, but clearly the contract win is another positive development for Open Orphan's business model, with challenge model revenues now expected to exceed financial year 2022 levels," Brewer added.
Meanwhile, Thomason said: "Momentum continues to build, and prelims in September (projected) will give good granularity of the progress made to date with management guiding to GBP50 million of revenue in 2022."
By Sophie Rose; sophierose@alliancenews.com