RE: Daily Mail p137 Jun 2020 17:15
the bit at the bottom gives more hope to us.
“All this work has been done unusually quickly,” Prof Hill admitted.
But a trial of the vaccine in rhesus macaque monkeys did not stop the animals from catching the virus and has raised questions about the vaccine's likely human efficacy and ongoing development.
"All of the vaccinated monkeys treated with the Oxford vaccine became infected when challenged as judged by recovery of virus genomic RNA from nasal secretions," said Dr William Haseltine, a former Harvard Medical School professor who had a pivotal role in the development of early HIV/Aids treatments.
"There was no difference in the amount of viral RNA detected from this site in the vaccinated monkeys as compared to the unvaccinated animals. Which is to say, all vaccinated animals were infected," Dr Haseltine wrote in an article on Forbes.
But Prof Hill said the article was misleading because the monkeys had been deliberately “overdosed” on coronavirus in order to test for safety.
“The honest truth, I think, is that the author is a long-retired senior Harvard virologist, infectious disease guy. He's not a vaccine developer,” he said.
“We used a really high dose and these guys gave it not just into the lungs and the nose. They gave it into the mouth, and they gave it into the eyes. They gave a huge dose. I mean, seriously, it’s that level of basic.”
Even so, Prof Hill accepts the chances of success still hang firmly in the balance.
“The US government, the UK government, loads of charities and philanthropists are all saying we’ll pay to have it manufactured, before you finish the trial. I mean, it's a huge kind of vote of confidence in what we're doing. It's really flattering,” he said.
“But that doesn't guarantee the result. It could be nothing or could be great or somewhere in between."
If the vaccine works we don't become a billion dollar comapny only a 200-400 million. Yes I know they have only tried it on young people at the moment and the real problem is if old people get it so its still up in the air at the moment. (when saying works I meant for everyone)
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