Member Info for drshaggy

http://www.telegraph.co.uk/news/2016/05/03/germany-to-legalise-cannabis-for-medicinal-purposes/

Facebook's mobile ad revenue surged 50% in the last quarter according to reports. Meanwhile Blinkx dies a slow death...

If it's any consolation I'm 83% down as well. At least we won't drown alone. Every call I've ever made on this share has been wrong, so no advice I'm afraid.

http://www.militarytimes.com/story/veterans/2016/04/21/dea-approves-ptsd-marijuana-study/83356604/

.. an interesting development concerning the production of cannabinoids over in Canada: http://www.cbc.ca/news/technology/medical-marijuana-yeast-1.3527950

Medicinal extracts approved by the FDA I reckon.

They'll reschedule medicinal cannabis extracts only IMO.

Pensioner will no doubt be telling us that BM's doing a wonderful job, just like he has been for the last 2 years, during which time we've seen the share value collapse to its current level. Still, I'm sure BM's doing well out of it all. Me. I wouldn't hire him to tend my toilet.

PS: I've been censored but I think people know what I mean.

If Tosca had any sense they'd dump their shareholding and take the hit. It looks to me that Tosca's been sold the same pup by BM and are in deep**** along with the rest of us. One useful thing they could do though is force BM out.

I think his name should really be Fullo****.

I've said it before, I'll say it again, BM is overpaid and has consistently underperformed. He needs to go.

... reported an open short of 0.71% adding to those by Oxford and Partner Fund according to today's FCA update. That highly negative 'report' over the Easter weekend in combination with the short selling yesterday has all the hallmarks of a more co-ordinated short attack than those previously opened on GWP. We'll see over the next few weeks I guess. All IMO of course.

Mechoulam is now also a R&D Collaborator for GWP: http://www.gwpharm.com/r-and-d-collaborations.aspx

It's interesting that Zynerba make reference to the following publication about CBD as an potential anti-epileptic compound: Consroe P, Wolkin A. Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats. J Pharmacol Exp Ther. 1977 Apr;201(1):26-32. Note the date: 1977. CBD as an anti-epileptic has been known for years. Here we are 40 years later and this is only now finally been confirmed/acknowledged and acted upon. Having cannabis on the Schedule 1 has clearly caused immeasurable and unnecessary human suffering, all because of the politics involved.

Those miscreants who drug drive have been known to temporarily reduce the pollution levels by using chlorhexydine (Corsodyl) or some other mouthwash. Some even carry a bottle in their glove compartment so that if they're stopped they can have a quick swig to clean the mucosal surface and stimulate saliva production before being tested. Chewing gum can stimulate saliva production of course. Some people always chew when they drive to reduce contamination. The use of alcohol reduces oral contamination as well, especially if stronger alcohol is used. This is because THC is soluble in alcohol. Cannabis users who drink alcohol have less contamination than those who don't drink. The police are supposed to wait 15 minutes before taking a roadside drug test, in case someone's been chewing gum/ eating or drinking, therefore temporarily reducing the level of contamination. It's said that Corsodyl/mouthwashes reduce contamination for up to 30 minutes.

This depends on several factors. As a general guide the manufacturers of oral testing kits claim to detect ACTIVE THC for up to 12 hours in the mucosal cavity after smoking/vaporising a single joint/bowl/balloon. However, what's less clear is the cumulative pollution caused by smoking on a regular basis, which leads to a build up of THC in the oral cavity which over time can exceed the limit days after initial ingestion. This means that a regular smoker will always exceed to 2ng/ltr drig driving limit. Other factors include oral hygiene, in that those who use chlorohexydene, mouth washes and brush their teeth more regularly can reduce oral contamination (at least on a temporary basis). These activities stimulate saliva production which temporarily reduces the concentration per litre Transdermal patches and suppositories bypass the oral cavity, and so wouldn't be detectable in a saliva test at all (because THC isn't soluble in water. Pollution by edibles would vary depending on how long the edible stays in the mouth during mastication, whether it's extracted in butter or coconut oil, or 'bombed' without the contents touching the mouth (concentrated solidified cannacoco oil wrapped in rizzlas for example). So the answer to your question is if its regularly ingested in such a way that it comes in direct contact with the oral cavity then it will be perpetually polluted and will fail a drug driving test. So, having a level that exceeds the current drug driving laws does not necessarily mean that you need to have smoked within the preceding 24 hours. With a very heavy smoker the level could exceed the limit for over a week later even with complete abstinence. The drug driving limit bears no relationship with actual impairment of course. The Wolff review on behalf of the Government recommended 5ng/ltr as a minimum, but the Government overruled Wollf's 'expert' advice and opted for a limit that was well below the agreed impairment level instead (effectively zero tolerance).

Even if it were true, they wouldn't fail an initial roadside drug driving test here in the UK because the oral saliva test doesn't measure THC in the system, but only measures THC contamination/pollution in the oral cavity itself. If they've only taken CBD then the oral cavity can't be polluted with THC, so they'll pass the test.

PPS: If cannabinoids are extracted using coconut oil (as opposed to say butter) they can be eaten and and more effectively absorbed because coconut oil bypasses the liver. There is, however, still some loss in the gut itself. Of all the edible routes, coconut oil is the best for this reason.

PS: although the suppository route improves dosage efficiency it's been reported that for some reason the psychoactive effects (of THC) are reduced by this route. People who have problems with the psychoactive dimension of cannabis oils are often advised to take suppositories instead.