RE: Big Pharma protection ??24 Mar 2016 09:20
Absorption through the skin, like through the lungs, oral mucosa or rectum, means that CBD (or THC) can be absorbed into the system without having to go through the gastric route and then on through the liver - which results in a marked loss/reduced dosage and so is more inefficient than the other methods of delivery. That's why GWP have gone down the oral mucosa delivery route, Zynerba transdermal patches, because the gastrointestinal route can't offer the kind of 'precise' dosage parameters demanded by the regulatory authorities.
That's why Sativex is formulated as a oral buccal spray - to avoid dosage loss
In the medical marijuana community precise dosage isn't an issue, so cannabis oil extracts are usually taken orally, the sheer quantity of cannabinoids overcoming the inefficiencies of absorption through the GI and liver.
People who use the same cannabis oil in the form of suppositories get a much higher proportion of the dose than those who simply swallow it.
I don't think that CBD is secretly psychoactive, so I don't think you have anything to worry about there.