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AZD1656 in Transplantation With Diabetes tO PromoTe Immune TOleraNce. ClinicalTrials.gov ID NCT05216172

Last Update Submitted that Met QC Criteria = 2024-06-18

https://clinicaltrials.gov/study/NCT05216172?tab=history&a=5#study-status-card

IMO The regulatory environment plays a significant role in the delay. SYME needs to navigate securities laws, financial reporting requirements, and other regulatory frameworks to ensure compliance and transparency.IM transactions involve multiple stakeholders, including clients, investors, and financial institutions. Aligning the interests and requirements of all parties whilst complying with the above has always been and is still the Achilles heel of SYME. Transparency and trust are married, without it, separation is inevitable.

Not one RNS celebrating SYME meeting Legal compliance or other requirements has published. Perhaps a question at the AGM by those attending.

GLA

Chill out guys we have a basic time schedule. Whether you buy sell or hold is a personal choice and importantly should be detached from sentiment or influence.

Average brain sizes have shrunk over the course of the last 100,000 years, deterioration appears somewhat advanced on most chat boards.

Favourite Quotes: “A lie gets halfway around the world before the truth has a chance to get its pants on” (Winston Churchill). “No one can make you feel inferior without your consent”(Eleanor Roosevelt).

The arrival of the kiln marks a significant milestone, and the next stages involve installation, commissioning and testing. Here's an overview IMO of the expected next steps. I'll let posters guess the timescales :)

Installation of Ancillary Equipment: Setting up infrastructure and components to support the kiln's operation. Carried out by Engsolve.

Commissioning and Testing: Once complete, the R&D team will start commissioning and testing the kiln including Feedstock Testing Unit (FTU). Involving calibrating the equipment, optimizing performance, ensuring all systems function as designed.

Research and Development: The kiln will initially be used for research and development purposes, testing various waste streams, optimize the conversion process to gather data, refine their technology, and showcase the capabilities to potential investors and customers by providing tangible evidence of its effectiveness and potential benefits.

Scaling Up and Commercial Operations: Following successful commissioning and testing, PHE will focus on scaling up their operations. This includes building additional FTUs, establishing partnerships, and securing contracts for the deployment of their technology at a commercial scale.

Continuous Optimization and Innovation: Throughout the process, PHE will continue to optimize their technology, improve efficiency and explore innovative updates including remote management.

Regulatory Compliance and Permitting: As as in commercial operations, compliance with environmental regulations and obtain the necessary permits for waste-to-energy facilities.

Market Penetration and Expansion: With a proven technology with IP and successful demonstrations, focus will shift to penetrating the market and expanding their reach for new customers, industries, and geographic regions, showcasing the applicability and benefits of their waste-to-energy solution.

Long-Term Sustainability and Impact: Ultimately, PHE aims include reduced landfill waste, minimize environmental impact, and support the transition to a circular economy.

dear paul, please get that kit fired up asap, folk here are going limp...

https://www.independent.co.uk/news/uk/home-news/microplastics-*****-erectile-dysfunction-b2565206.html

Is how small those fire extinguishers are....

National H2 is one of many within the United conglomerate (circ 37). Not seen any funding or any other news since agreement on what is a basic letter of intent. Suggest some need to get one of these to go down to the pub.

https://www.designboom.com/technology/foldable-sport-rental-hydrogen-bikes-water-tanks-hydroride-europe-hyryd-06-18-2024/

DYOR

PHE’s Chief Executive Officer, Paul Emmitt, explained the collaboration with National H2 represents several years of work, discussion and negotiation with the Australian company’s chairman, Richard Allen.

Interested but not too concerned re Longford or OZ. The real Ace is World IP, paramount before proof of delivery, whether Ireland or OZ, otherwise PHE will end up with more contesting court cases than Trump.

IMHO beyond 2p perhaps, but PHE may suffer growing pains until further IP confirmation and commissioning at Wales site not forgetting H2 funding and contract closure leading to spades in the ground. Note: There’s a lot of hoops to climb through e.g.: Plant testing, process control algorithms adjustment, verification via independent analyst's whether for efficiency or environmental status. Technical: https://safetyculture.com/topics/commis sioning/

So Patience required, being a stickler for detail I’m prepared wait until every box is ticked before a true valuation becomes apparent. Guess that makes me a LTH :)

Https://www.proactiveinvestors.com/companies/news/1048676/hydrogen-utopia-receives-details-that-could-have-material-effect-on-takeover-target-1048676.html

I have had a very prompt and polite reply from PHE regarding my interest of remote monitoring of (DMG) Installations. I am pleased to share with you that IOT will allow PHE to continually remotely monitor and improve the DMG process post installation with the ability to implement upgrade packages and indicate predictive maintenance.

The royalty as part of any licence agreement IMHO is a crucial USP, allowing system controls for various feed stocks and required outputs to obtain peak performance which is paramount to all concerned. Not forgetting the line "Many thanks for investing"

Spread changing on every refresh. My word they are busy...

Allaboutbucks: Can’t disagree with objective analysis apart from “waffle” LOL. IMHO Syme’s have always been too keen to drop big names to early into RNS when their platform is not meeting all the criteria required by partners. It all seems back to front. I’d Prefer to have named criteria, completion and compliance publicised. Only when the platform ticks all the boxes should they release named financial partnerships. SYME would then demonstrate structure and generate confidence rather than the current stick a patch on it approach.

Still believe it can be done if they can stop chucking out the baby with the bath water.

GLA

Sharebel: Tradeflow Capital utilised p-Chip's technology years ago after engaging in case studies along with Walmart, Merck, IBM, FedEx etc. Disappointed as asset monitoring and asset tracking through IOT was on the list years ago. Major IM Capital won't commit without authentication, whether E.G. agriculture to track and monitor location, temperature, humidity, and other environmental factors in real-time. Basically, its boils down to accountability through verification. Shame it’s taken so long...

Hey hang on there Castle I object to that statement... I've had many happy years poking around under blankets.

OOPS Perhaps I should have used the term “thermal decomposition”. PHE have stated that the DMG process reduces carbon content recovered as biochar. Not clear on validity for specific feedstocks. Its potentially an additional revenue stream and If correct a soil amendment to improve soil fertility and seize carbon. They’ve got to get it right at both ends, I don't want toxic tatties.

30silver: Thank you for your in-depth explanation of the syngas process with special regard too longevity of process, Down time/maintenance. I understand the temperatures within Town Gas kilns had an average life of 10 to 15 years before major refurbishment.

That said, I politely challenge the stated 24-28 hour cycle before shut down for maintenance. To clarify PHE cannot claim IP on pyrolysis but can and are with control systems, an essential part of the design maintaining efficiency and kiln longevity.

No mention of Plastic or tyre's, but Is this a concern?

https://processandcontrolmag.co.uk/uk-firm-to-boost-ukraines-energy-security-with-pioneering-waste-to-power-plant/

JoeyBloggs7: Even AZD1656 in Transplantation With Diabetes, Queen Mary coming up to a year without movement. https://clinicaltrials.gov/study/NCT05216172?tab=results