Member Info for davidpqz

It was simply based on the follow ups were at 18 days and two months. 17 days is monday from the 'last week' and so is probably too high. The negatives here are that a cohort size of three is tiny and the results may not be reproducable. It may also be the case that the improvements do not last. Against that the improvements were very pronounced. I also suspect that if the improvement is not permanent then a big pharma company might throw money at the problem. Anyway, you pay your money and place your bet. Good luck all (especially the patients).

On the 18th they stated that the first patient had been treated 'last week' which gives a maximum of 17 days. I don't think that's long enough.

Does anyone know what has triggered this? Has there been piece in the press about the RP results?

It may not be possible to put a figure on risk however it is possible to consider comparative risk. Clearly this situation is much less riskier than a company drilling for oil and facing the possibility that the well is dry. The risks with HUR as others have mentioned, are to do with porosity. As the Lancaster field is around 200 million years old and Bach Ho the producing fractured basement field in Vietnam is about (from memory) 70m years old, it is quite likely that Lancaster is in fact more porous than the former.

A google search will bring up some examples of this chart. It is much more demanding than the standard eye test chart.

I see the spread is shrinking as well. You had to be very confident to buy on an 8% spread.

As a firework loving kid in the 1950's I feel qualified to make a minor correction. A banger did just that - it exploded with a bang. A squib you might describe as a ground rocket , it jetted around a ground level (no H&E then!).

https://luxturna.com/about-luxturna/#who-is-luxturna-for
LUXTURNA is for individuals with an inherited retinal disease caused by mutations in both copies of the RPE65 gene and who have enough remaining cells in the retina

The Luxturna treatment is specifically for the inherited RPE65 gene defect. This is from https://luxturna.com/about-luxturna/#who-is-luxturna-for and indicates that it is not a treatment for RP.
"There are many inherited retinal diseases " ...
For example, Leber congenital amaurosis and retinitis pigmentosa are two inherited retinal diseases. These are clinical diagnoses that are not based on mutations in specific genes, such as mutations in both copies of the RPE65 gene.

Very promising early stage CRISPR research into curing RP. Has anyone researched other contenders who might snatch the prize?

No. It was me.

Just one small observation. The forecasts for sea conditions WOS seem to be very changeable (chorus of derision from old oily sea salts). So, although Wed-Thurs is currently looking good do keep an eye on it. I'm off to Venice for a few days and hope we don't get any 'high water over there.

The main negatives for this share are a) its wide spread and b) the fact that something like 80% of it is owned by an investment fund. On the other hand, with a forward PE of only 5.5 I think these are fully factored in. Someone was saying (probably over on Stockopedia) that in the last few years nearly half of his purchase price has been returned in dividends.
I'm certainly happy to hold.

Apart from that, the only visible window is a short 12 hour period on the 7th of march.

The window is midday today to midnight tomorrow. I think it takes about 30 hours (correct me if I'm wrong) to get up to Lancaster.

Height of swell needs to be 2m or less.
https://marine.meteoconsult.co.uk/marine-weather-forecast/marine-coastline/british-isles/weather-forecast-coastal%20areas-west-shetland-14938-10.php

Don't think so. Max swell height is 2m.
https://marine.meteoconsult.co.uk/marine-weather-forecast/marine-coastline/british-isles/weather-forecast-coastal%20areas-west-shetland-14938-4.php

There isn't a guidance figure for 2019 which is irritating. However by using their total geo figure and guidance prices I make it 156,000 ozs or about 25% down on 2018. Any views?

Nice indeed! I believe this has the lowest AISC of all the gold miners. The sp has been range bound for a while. Does anyone know why it has broken out now?

Nissan, Airbus, Sony, M&S, Barclays ....

I'm not new. I just don't have a massive ego and the need to shoot my mouth off every 10 seconds. Bye.