Member Info for Dalester

Hi Ruck, any Vaccine (or anything else) is worth what people are prepared to pay for it. HMG are involved with a group of other countries and have already promised £200m or thereabouts towards developing a vaccine. They want to G20 to put in at least £100m each. They expect to pay a lot for the right product. If scancell pitch a £30m solution they are unlikely to be taken seriously. Big money buys security for people making the decision. I have been through this loop on a number of occasions... the old adage "no one ever got sacked for buying IBM " applies equally well to most Government contracting. I once proposed an IT training solution to the NHS for £10m all done and dusted, then they brought in "consultants" from one of the big accountancy firms and ended up paying over £300m for something that was hardly ever used, just because it came from a big US IT name. They could have built a new hospital with the money they wasted! Simple fact of life is you can easily reduce a price, it's not so easy putting one up.

Given that the expectation of the cost of producing a new vaccine is $500m and upwards, there is room to do a deal that is well within those expectations and yet provide Scancell with an excellent reward for their expertise and IP , Its not as if governments are going to reject the best fix for the problem for the sake of a few million dollars ( assuming Scancell are in the equation). My experience of government contracts is that the more they spend the more secure they feel in their decision.
No one in government is going to say "no" if Scancell say they want $4 -500 m to stop this disease. At that point Scancell may waive any further payments other than manufacturing costs and leave distribution to someone else if they are going to give it away.

Why they cost so much, Covid 19 specific and a very straight forward explanation of each step along the way by Dr. Jerome Kim, the Director General of the International Vaccine Institute (IVI). Also good description of why you need antibodies and T cells in the process.
https://youtu.be/5cYWd0N8nO4

My bad, long term then. but I guess it depends how old you are when you get the jab! even so, I think long term sounds to be a much better option than "please come in on Saturday morning for your booster jab" every 6-12 months. Imagine all the follow up that will be required if its an annual jab.

I think its a given that if there is a way of giving people a one-time vaccination against this horrid little virus, the Government would be keen to use it rather than have annual outbreaks because lots of people didn't turn up for a booster jab or thought the whole thing had gone away. it also puts Covid on the back burner as far as potential threats are concerned. Most developed economies would be thinking the same thing as another economic hiatus in the next decade or so would be virtually unthinkable. It looks to me that Lindy has once again thought something through a bit more than some of her contemporaries and maybe sussed a better way!

And therein lies the problem, the science is fantastic the commercial managemen is utterly lacklustre. I will keep bangingnthis drum..... the science is complex and the marketing and PR needs to present that science in ways that is easily understood. Most LTHs have got their heads around it, eventually but a new investor needs to know why he/she should invest here rather than following the herd and why he will need lots of patience! Lindy needed to do the "elevator pitch" on the radio stressing them long term benefit of the Scancell solution against further Corvid epidemics and the fewer, if no, side effects etc. The case for investors being that this solution will be prefered as a one time fix with repeat doses probably not needed. Its frustrating to so often get into a relatively good place and then somehow manage not to capitalise on it, its like scoring an early goal and then giving away a soft penalty just before half time, not game over but back to square one.

Interesting comment about being behind other potential vaccines from Lindy " I think we can catch up". This is not an easy thing to explain on the radio, I doubt many listeners will be any the wiser... antigens this, T Cells that, most people just want a jab and get back to work.
Scancell really do need to put some effort into simplifying the presentation of their technology if there is any value in having it understood by the vast majority including a lot of potential investors

There is some truth in the UV light inside the body idea, watch the video: AYTU is listed in the US and partnered with Cedars Sinae Medical Centre
https://aytubio.com/healight/

Oops , twitched and posted before completion! Just saying that we have waited ages for some news that has real impact on the SP and as soon as it arrives we start pulling it apart rather than just applauding the decision . I dont think we should try to overthink this, Lindy does not seem thr type to get sidetracked on a whim. To take resources away from her desire to conquor cancer, she must believe sha can make a real difference . If she does, and the board support her I am happy to fall in line Friday was the best day we have had for ages, a foretaste of what Scancell is capable of doing . Lets not spoil it for the sake of a few rounds of point scoring off each other.

Aftternoon everyone. Wouldnt it be great if we could all get behind the decision made by the company to produce a vaccine to combat this virus?

Anyone got any thoughts about if graphene would help this process?
https://3dprintingindustry.com/news/u-s-army-develops-high-strength-multi-polymer-filament-for-use-with-low-cost-3d-printers-171038/

I hear the cheaper argument but it smacks of someone in the purchasing department being penny wise and pound foolish. For example, how many extra sets of instruments did they have to buy to cover the time it takes to ship sets back and forth? How often can they go to India to check the quality of work there and what is the fallback position if they dont measure up?
On the subject of washing, I think some hospitals still have their own laundries, but I imagine many farm out their washables.
We need to become far more self sufficient in the UK , being in the EU for 50 years has done us no real favours wih 1000s of acres of land "set aside" and many key functions being run by foreign companies including Greater Manchester trams and traffic lights. Its time for the UK to start the process of reclaiming our own destiny in what seems to be an increasingly uncertain world. I dont want to be in a low skill low wage economy, I want to live in a smart, highly skilled highly efficient country where penny pinching is a thing of the distant past.

I have been advocating for a while that a £130Bn a yesr organisation shouldnt be dependent on buying critical equipment from overseas suppliers. There is plenty of money within the NHS to have its own factory making PPE , adding Graphene into such an operation would enable it to be come a world leader and as such a profit centre. There are plenty of empty factories in the North and there is a workforce ready to get started. New skills, new jobs, security of supply , what's not to like?

From the Guardian Sept 2019
"NHS hospital trusts are being crippled by the private finance initiative and will have to make another £55bn in payments by the time the last contract ends in 2050, a report reveals.

An initial £13bn of private sector-funded investment in new hospitals will end up costing the NHS in England a staggering £80bn by the time all contracts come to an end, the IPPR thinktank has found.

Some trusts are having to spend as much as one-sixth of their entire budget on repaying debts due as a result of the PFI scheme. PFI was introduced by John Major’s Conservative government but its use proliferated in the Blair era."

The NHS also has £83.4 Bn in reserves in case of being sued for negligence according to last years accounts, enough to buy its own factories making whatever PPE it needs and pay off its PFI debts. (In 18 /19 , negligence claims amounted to just over £2 Bn and yet they added £6.2Bn to the pot).

Good Call C7,.......... what numbers have you picked for the lottery?

People with flu jab may have 36% increased CV risk
https://www.disabledveterans.org/2020/03/11/flu-vaccine-increases-coronavirus-risk/

One of the major problems must be the density of population , the UK has the highest density in Europe, cities like London and Milan will inevitably be problematic and in the long term the UK may well suffer more than Italy simply because more people live cheek by jowl.

It might be easier to sign up restaurants if there are owners sitting around twiddling their thumbs .

At the end of WW2, the stock market was higher than it was before the start.

Evening C 7 not sure that this is airborne in the sense that you could catch it walking about in your garden ...
This video explains the difference between droplet infection and airborne, big difference , its mor3 to do with proximity to,other people.
https://youtu.be/F1JEbx9NY2I