RE: Testing!19 Jun 2020 12:36
Actually if you take the https:// away it works. Seriously hard reading, most of it over my head. However I belive what they are saying is they can now look at viruses and other nano particles with far more detail than any current method, even if frozen. How this tech is developed and what monetary value it has I have no idea. However I can only imagine that many Pharma companies would love to be able to see viruses, bacteria etc at increased resolution even when the concentrations are low. The report suggests this imaging sytem is hands down better than current sytems, in terms of the ability to detec at low concentration, if frozen, higher resolution, less "noise" and more durable. The extract is super sciencey but I tried to give a flavour below. This will be a winner in terms of ALL virus detection.
Cryo-electron microscopy is an essential tool for high-resolution structural studies of biological systems. T with improved transfer at lower spatial frequencies, and as such is more efficient for phase recovery than conventional phase contrast imaging. We further show that the method can be used to study frozen-hydrated specimens of rotavirus double-layered particles and HIV-1 virus-like particles under low-dose conditions (5.7?e/Å2) and heterogeneous objects in an Adenovirus-infected cell over large fields of view (1.14?×?1.14?µm), thus making it suitable for studies of many biologically important structures.
Our ptychographic phase reconstructions of rotavirus double-layered particles (DLPs) and non-symmetric immature HIV-1 virus-like particles (VLPs) in a cryo-state show excellent phase sensitivity and improved information transfer particularly at a low spatial frequencies under low dose conditions.