The Day after31 Jul 2021 07:42
The night before...A few too many snooty bermuda shots were had and off came the shorts..... rest is a blur:)
Anyways from the jail cell.... An interesting article by prof Bent of Continuum I've C n P'd the most relevant for us part here:
'Approximately ten years ago, a small number of treatments based on directing the immune system against cancers began to show promise and we therefore now know a good deal more about the immunological mechanisms involved in targeting cancer. At the same time, the science and technologies available to analyse immune mechanisms have undergone a revolutionary development. Continuum has, over the last few years, made excellent use of these developments by placing research projects in world-class UK laboratories.
Investigating samples from long-term cancer survivors, these laboratories have identified novel and unexpected immune mechanisms that are only present in these rare types of patients. The implications are potentially enormous: If these mechanisms from long-term survivors can be understood and turned into drugs, it should be possible – in patients whose immune systems do not by themselves react powerfully enough – to induce control of the cancer. Thus, the hope is that we will be able to turn patients with progressive disease into long-term survivors.
Continuum is at the stage when research must be turned into treatments. This involves a huge amount of testing for efficacy and toxicity, drug manufacturing, and design of clinical trials. Therefore, Continuum is setting up its own Research and Development facility and recruiting a world-class team of experts in immune oncology to bring entirely new types of treatments to patients. In a few years’ time, the first novel drug candidates will be tested in patients, and I believe we will begin to see the immune mechanisms that keep a very few patients alive for the long term begin to benefit a vastly larger number of patients.
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