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Abstract B104: Post-translationally modified homocitrulline induced by MDSCs can be an effective antitumor target for CD4 T-cells

http://cancerimmunolres.aacrjournals.org/content/7/2_Supplement/B104

Or a seller I can't tell...which what they want!!

Nein.. well not yet anyways... must have spent up their Oktoberfest funds lol

A lot of us in the deep end...all I can say is it can turn around here very fast and we do have the potential of coming positive newsflow to do that.... the alternative is drowning:)

I know talk about the most extreme example lol! ... SCIB1 combo going off human data we already have should have no SCIB1 related side effects though probably some Keytruda ones... and the Ichor does leave a nasty bruise...as for modi1 Its going through preclinical tox tests now.. Though till trialled in humans we will not know of any 'hidden' side effects but it is a vaccine so I very much doubt there will be anything too bad and it will be the trial patients last chance... so here is hoping it does what it could... Lindy has sounded more and more confident about it every time I have heard her talk about it...

It is a real-life horror story

https://www.bbc.co.uk/news/magazine-35766627

that one

Yes, that was an infamous trial... I understand the survivors are still living with the consequences... see that is what happens when you turn the immune system against self... when you can harness that power against cancer only though...wow

And great to have you here :)

What?...late stage patients... you know if moditope works.. it means terminal patients stay alive with tumours melting away like ice cubes in the sun... in very hard to treat cancer targets... think you do not know what you are invested in?

Trials are actually very short lol... data within a year...

Ruck I think it is our best 'hope' lol at least the one we know about... but I do not see it as a distraction at all over a year in BioNtech labs... get a deal after that the validation would be massive... add in massive valuation and we are away! :)
well with current mcap even one target at $8 million upfront would be 'transformational'... do think if it is done we will do better than that though...

But the BioNtech collaboration is real lol... in an RNS began last year ends H1 this.... no we cannot say 100% it ends with a licensing deal... but as C7 Samantha has been brought in to work on 'new TCR theraputics'...which is encouraging so let us see...

Two trials planned to begin this year SCIB1 keytruda combo in US/UK H1 and modi1 in 3 cancer targets UK H2

BioNtech and the 'new TCR theraputics'

We always need luck... but in an investment like this, we need great science too ...It would be wrong to think the sp is an indication of the value of the science it is not as the science has not been valued yet... it is also not an indication that no one from outside of scancell is interested in it.... we are possibly fast approaching a BioNtech licensing deal.... plus who knows what...but we know Genentech are aware of and impressed by scancells tech... namely moditope too....

Yes, it does seem they have that 'scattergun' approach... having said that we could do with some of what they have plenty of... dosh lol

Xencor to Develop and Commercialize Novel IL-15 Immune Activating Cytokines with Genentech

-- Xencor Receives $120 Million Upfront Payment, up to $180 Million in Development Milestones Per Program and Profit Share from Commercialized Medicines

https://www.prnewswire.com/news-releases/xencor-to-develop-and-commercialize-novel-il-15-immune-activating-cytokines-with-genentech-300789601.html?sf98437132=1

Genentech not holding back on splashing the cash on immuno onco deals this year!

I agree with that Cars... you not only get valuation ...in our case of a product in setting beyond its original - TCR but we would also get that all-important validation from a very respected source who everyone would also know has been working with moditopes for over a year.... it would you would think cause the phone to begin ringing :)

Nobody has bought anything there for soooo long... I check almost every day but since the 31st.... someone seems to be... and that is all really, nothing else... Again it is wrong to read anything into it... was having a bit of fun wondering if you worked for a German bio about to do a deal with a UK one that happened to have German listing maybe you would buy a few... Till an RNS arrives confirming it we just go off certain facts.... such as 'new TCR therapeutics' as Lindy said and what Cliff said about taking the BioNtech collaboration forward in his youtube vid