NIH releases H5N1 influenza research agenda5 Jun 2024 19:46
So they need 'broad-spectrum antiviral drugs with novel mechanisms of action'. Hmmm. GLA
'Objective 3: Advance existing and novel H5N1 influenza treatment strategies
Antivirals are considered a first line of defense for controlling novel influenza virus outbreaks, as little immunity is present in the human population and vaccine development is a prolonged process. NIAID is developing and testing safe and effective antivirals to treat influenza infections and prevent serious complications.
• Focus Area: Direct Acting Therapeutics
The emergence or re-emergence of influenza viruses potentially resistant to existing antiviral drugs is a serious and ongoing threat necessitating the development of new, broad-spectrum antiviral drugs with novel mechanisms of action and host-directed therapeutics to treat influenza. NIAID will continue to investigate the safety and efficacy of broad-spectrum direct acting antivirals. Additionally, pan-influenza host-targeted molecules that can target multiple influenza viruses are being evaluated.'