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One2, what does the following mean please?
''my target was to stay until the patients went into remission sadly this is not going to be hemogenyx as other pharms has proven the car-t science has been proven thou again openly being honest the next rns will be dismal & the sp will drop like a jack russels butt with worms''
are you saying CAR T already proven so HEMO CAR T of no value - who has proven CAR T with AML?
thanks
Yet again Radio 4 this morning reminding of the power of CAR T therapy,
(after chemo and bone marrow transplant didnt respond).
I dont feel the benefit of this therapy is a secret in the science world (and beyond) - far from it.
Just need the CH lifted...
One2
was curious why you didnt respond the Hemoknowlede on 21st July?
''@one2one the drug from Daichi (quizartinib) targets FLT3-ITD mutated AML. These are 25% of all AML patients. This drug reduces mortality of these patients by 22%. This drug cannot be used on its own but only in combination with standard chemotherapy. Science does not really move on far in this case''
Interesting links.
are we speculating that the data already provided by HEMO shows a higher probability of side effects compared to other CAR T treatments - if so how do HEMO address that given this is a novel CAR T...
(CAR-NK appeared to be effective BUT many patients received subsequent treatments (like chemotherapy) soon after the CAR-NK therapy).
I think we all accept we want to get HEMO CAR T into clinical trials asap but in the grand scheme of things, if its within 6 months from now, (fingers crossed), is that really a big deal - are other treatments for AML going to leave HEMO for dust - Im not convinced they will. If HEMO can reduce arm to arm time as the trials progress then great - but the most important thing of course is that patients go in to remission with minimal side effects...
IMLHO
peace
Great post at 9.07 Hulver.
I guess this boils down to whether you believe Vlad will resolve this or not.
Im happy to average down - potential reward still significantly outweighs the risk for me.
We can all write on here what the hell we want - I dont believe is makes a jot of difference to the sp - sentiment has been hit so the herd move on - but if Vlad sorts this in the next six months the herd returns...
This is his life's work and he has brought in experienced specialists to assist in getting him to this point - I cannot see how he would let this fail now...
peace
Https://twitter.com/tmsreach/status/1664672451639246867?s=11&t=CwZpHUZhFOIY6BSujEHaLg