Member Info for cj62

I have been having a quick glance through all the approved ADC's and there is still a severe problem with side effects then the costs are quite astronomical in some cases. The improvent on PFS is not all that great and AVA 6K has surpassed the best already with no MTD which the ADC's still have.

Anyway enough for the day and thanks JT for stopping me being lazy.

JT Thanks for that but there are now 15

Table of Contents

Structural characteristics of ADCs

Antibody-drug conjugates – mechanism of action

Approved ADCs

Mylotarg

Adcetris

Kadcyla

Besponsa

Lumoxiti

Polivy

Padcev

Enhertu

Trodelvy

Blenrep

Zynlota

Tivdak

Elahere

The 1st mylotarg £10k for 1 injection and the list of serious side effects is endless.

Are all ADC's proven ?

So Sujood you have just admitted you have been spewing utter tosh for ever. Thanks now can you stop altogether as it doesn't help anyone.

We're doomed !!!!!!!!!!!!!!!!

100% record intact I see 🎉🎉🎉

An RNS guaranteed in the next 6 months 100%

No need to thank me folks but you heard it here first

No

Conspicuous by his absence though Timster !

I wish life was that simple

I have boiled eggs for breakfast on a Wednesday, the point is ?

It's Tuesday!!

Bang on again Sujood 100% failure rate, God I wish I was as useless as you.

Forgive me Sujood for not getting overly excited with your latest prediction.

Bella he needs to get a wiggle on as the clock is ticking regarding funding and its very easy to say " don't worry" especially when you are earning £500 k a year.

I am patient but we need to know which way we are heading.

Anyway when is cohort 7 going to conclude?

VS. I say 4-6 months as I am estimating completion of the fortnightly dosing.

What AS has up his sleeve is a mystery but let's hope its something that avoids a cash raise.

Ideally a licence deal with £100m upfront and billions in future milestone payments. That would get tid of HCI and enough cash to get through phase 2.

Then I woke up 😬😬😬

I would say 4-6 month but we could get a curve ball sooner.

Perhaps they are seeing something that warrants it. Tumour reduction for 1.

C7 has been going for a while now

Just a thought but could avacta just keep cohort 7 going ?

DTW well said but the sp languishing still makes me question my investment. We have the HCI shares shortly which will pressurise the sp further .

My major annoyance is not having spare cash to buy more as the Taxman is presently more pressing