RE: Even better results if taken early29 Apr 2020 22:17
Jack, the piece that you are referring to it this,
'testing for confirmation of COVID-19 is currently being done at hospital laboratories and results are taking 24-36 hours to come through. We are finding that patients often have had COVID-19 symptoms for an average of 7-10 days by the time they are admitted to hospital. Ideally we would like patients to receive the first dose of study medication as early as possible into their illness to give it it’s best chance of working and to stop the further spread of the virus, therefore waiting for a further 24-36 hours after the patient is admitted to find out the hospital laboratory results is not ideal.'
That is the first amendment to the document that allowed point of care testing so they didn't have to wait 24-26 hours for confirmation of the infection before starting the trial.
That is not the justification for expanding the scope of the trial , which is the latest amendment.