When you unearthed Toukmoron as Derek, do you remember the initials of the person? And how sure are you that you weren't sold a dummy / fed a red herring / sent on a wildgoose chase?
RE: Heights cap selling from 118p13 Feb 2023 10:24
TheTwat has predicted 120p, then 130p then 160p (that post now gone) and is bashing hard today so I guess he's being paid to drive it down to 160p, his masters being surprised by the strong support on the way down having given up on getting it to 120/130. Who's wanting to get in low or is still short?
So HC have been selling some 1,657,000 of their 3,068,421 repayment allocation at £1.72 per share in order to self-fund the acquisition of 2,400,000 more shares?
RE: Heights cap selling from 118p13 Feb 2023 09:52
HC received 3,068,421 on 24 January and will receive 2,400,000 on 16 February making 5,468,421 in total, which is less than 3% of Avacta shares in issue as of Thursday, so no TR1 required you moron.
Those 3 large prints at the end of Friday are about £62.4k short of £2.85m FWIW. That shortfall could be elsewhere in the listing of traders of course. If HC, then they wouldn't have sold all their holding. This could be a self-funding way to add to their holding before Avacta starts repayments in cash.
But are HC allowed to trade whilst they are privy to market sensitive information, assuming DD? According to SB, no, and that makes sense as it would clearly be insider trading.
RE: Only 2.4 mil as opposed to 3.068 mil13 Feb 2023 07:41
This wasn't a quarterly repayment. It was a decision by the loaner to convert some of the loan to shares at the conversion price, £1.1875.
At the quarterly repayment, Avacta has to cover to make the repayment in cash or shares. In future, even at the next repayment on 18 April, Avacta may be cash-rich enough to make the repayment in cash and the loaner would be locked out of receiving and further shares from the loan.
I regard that as extremely positive - licensing deal incoming!
I'll now go and have a laugh at what the basher clowns have been writing!
Rubbish! The key opinion leaders in oncology will be there to detail timescales to market and when the next products will be coming along plus any licensing deals in the bag ... according to Toukmoron.
RE: What data will be given for science day?12 Feb 2023 15:11
Toukmoron, you're a useless deramper. Just give it a rest and sit back and enjoy the ride everyone else is having ...which reminds me: that Kenny is one lucky guy ;0)
RE: Doxorubicin-Induced Cardiomyopathy in Children12 Feb 2023 14:03
From my reading around the topic, FAPa seems to be involved in tiissue growth and regrowth/repair/scarring and is described as being upregulated compared to healthy tissues and sometimes explicitly healthy ADULT tissues.
Can someone with knowledge of the science shine a light on the age/stage of growth when children stop significant upregulation of FAPa? The obvious assumption is when growth stops around 17 or 18 but that's only an assumption - if growth starts to slow, so may FAPa upregulation (i.e. there's no sudden halt to the upregulation).
RE: What data will be given for science day?12 Feb 2023 12:38
The mounted panto act is correct.
The conversion factor is 54/80.
This is because, going back to August 2021, Alan said the initial dose of AVA6000 of 80mg/m² was equivalent to 90% of the standard doxorubicin dose, which we took to be 60mg/m². This also matches up by calculating the molecular weights of the two.
So... 12 x 54 / 80 = 8.1 mg/m² of cequivalent So... 12 mg AVA6000 : 2 mg doxorubicin is 8.1 : 2 Or 4.05 times the doxorubicin dosing