Member Info for BBB11

Agreed. It's been an incredible 5 years and Vlad has performed miracles on a very small budget. He has worked hard to get here, and now we are only going one way... Upwards and patients will get their results.

Matt - did you read the below from Haywain? MD Anderson will release this soon, and it will be big news.

Aside from the required reporting of such events one thing worth remembering when thinking about P1 and P2 is that relapse risk in AML is very front-loaded. If a patient is going to relapse after achieving remission, it almost always happens in the first few weeks or months – because any surviving leukaemic progenitor cells will start repopulating the marrow very quickly. The fact that P1 is now more than six months post-HEMO-CAR-T and P2 is four months out with no relapse is hugely encouraging. Each extra month in remission actually makes it less likely that they will relapse, not more likely.

This is because CAR-T can generate memory T-cells that continue to patrol for any stray leukaemic cells. The longer a patient stays MRD-negative, the more evidence we have that either there are no leukaemic stem cells left or that the immune system is successfully keeping them in check. That’s why survival curves for CAR-T therapies flatten out over time – once you get past the early risk window you often see a “tail of the curve” where most patients stay in long-term remission and may effectively be cured.

So when you see P1 at 6+ months and P2 at 4+ months, it’s not just good news – it actually becomes increasingly powerful evidence that HEMO-CAR-T is doing more than just bridging to transplant. It’s showing the potential for durable, possibly curative remissions in FLT3+ r/r AML without HSCT.

Ask is jumping up with no live trades - institutions buying blocks by the looks of it. See big delayed trades later which will be buys

So as early as next week?

News of progression of trial and paediatric starting would be great

100% the shares are being bought up. Institutions have their price range to fill their big block orders and are happy to keep us here until there is some major retail investor push. Liquidity seems stable. The live prices or decrease is only private investors selling, e.g Alde. An RNS, or some buying pressure from retail investors that affect the share price immediately, would see this soar very quickly. We are in this space before another RNS or news pushes in live buying investors. Look at the size of the block buys, far outstrips PI each day. They are hoovering up the shares for the big boys

I've actually just topped up just a little bit... Think this has a lot of potential to be far higher.

Nice 40k buy

Mind me asking how much that was?

Understood, I still have significant north of £100k and holding. I think we are still awaiting a lot of good news

Aldebaran, assume you've sold? Looks like a PI selling a little not an institution.

We will hit £16 ask shortly... need some big buys to push past the resistance, but after that £18 is very easy to get to today.

Goodbye to shorters houses at this point.

Go short on a very low risk, likely cancer cure... I DARE you.

#billionsandyears

Not posting... You're talking rubbish.

HEMO was undervalued, that's why the raise came, after a rough biotech secror as a whole.

This news, and the potential, and lack of risk, means we should be a far higher market cap. 250m before other news sounds about right.

For anyone shorting - goodbye to your house.

HEMO are onto something special.

If this continues at dose escalation, then the media needs to pick this up big time. This will be bil+ market cap... Effeciacy for cancer is something noone should blink at. We may all need it one day.

Congratulations to HEMO on a great RNS... A few more great ones to come. This is only the start

I'll be buying my ticket to space if this continues.

Matt, copy all the trades of today, your question, the stock name, etc, and ask AI to give you an overview and teach you what manipulation has been done, what it means, and the likely rebound etc. Be far faster than us, teaching you via one comment at a time

Google just copies the very last trade, which includes the unknown/delayed trades, so it can show an outdated price. This will be back up in the morning. The volume was insane today, and far more buys than sells overall. Manipulation at the end, but if this had been open another 15 minutes, it would have rebounded as it had next to no resistance to get back to £14... Shorters going to short. £20 by end of week.

RMC - Given the 3 main RNS we are waiting for, are you seriously shorting this right now? You're brave, and arguably, taking far more risk than we are to reward given the expected news this week. You're in for a shock.

Steve talking rubbish. Plenty, if not most of us LTH still in, we haven't even had the news on P3 yet! Get your brain checked

Holy mother of god someone has deep pockets.

16:24:04 1,325.00 6,828 90.47k A

16:24:00 1,325.00 1,030 13.65k A

16:23:59 1,325.00 301 3,988 A

16:23:59 1,325.00 5,000 66.25k A

16:23:54 1,325.00 29 384.25 A

16:23:54 1,325.00 815 10.80k A

16:23:54 1,325.00 108 1,431 A

16:23:54 1,325.00 5,000 66.25k A

16:23:50 1,324.00 419 5,548 O

1.3m bought today. That is insane. Very nice to see this bought at these levels. 2X as many buys as sells.

3.10pm RNS anyone? Hahaha. This could skyrocket before close, little resistance with abit more buying pressure.