RE: Delta27 Aug 2021 13:10
WSJ - next bit
It took U.K. researchers and government advisers almost a year to plan and gain approval from a U.K. ethics committee and medicines regulators to start the controversial challenge trials for which the Delta strain could eventually be used. The government provided funding; so did the London-based Wellcome Trust, a large healthcare-focused charitable foundation.
The Wellcome Trust and Imperial College London will control the use of the Delta strain, including potentially sharing it with other researchers, Dr. Catchpole said. Meanwhile, he said hVivo and its partners also have a so-called Beta version of the virus, one that originally circulated in South Africa, stored securely in a freezer in case it is needed.
Imperial and hVivo said in May they had signed a £3 million contract, equivalent to around $4.1 million, funded by the Wellcome Trust to manufacture emerging coronavirus variants. It wasn’t clear then which variants researchers could successfully grow in the lab. A Wellcome Trust spokesman declined to comment. An Imperial spokesman said variant production so far hasn’t reached the standards for clinical use, but that work is ongoing.
The challenge trials faced pushback from some U.K. academics and foreign researchers, as well as from some government officials, who considered them unsafe or otherwise unethical, people involved in the process say. Delays have caused friction among partners. hVivo, part of London-listed pharma-services company Open Orphan PLC, ORPH -1.89% had hoped to use the Covid-19 challenge-trial model by now to test antivirals and other products for drug companies, executives have told industry peers. A U.K. government spokesman said the pace of the challenge studies has reflected appropriate caution, and the trials have been safe.