RE: Testing is here to stay! So you should do too5 Jan 2021 06:01
This is a really good question TWatcher. Given the RTC test was developed looking for a specific IgG to spike protein, and the spike protein has been modified in the SA variant, it is possible that it will impact the accuracy of the test for that use case. IF this new strain does manage to prove able to overcome the vaccine effort, and if the primary use case of the test is vaccine reaction, and if it becomes the globally dominant strain, then it would leave the test in a tricky situation. Not impossible, but a lot of unknowns at the moment. Some comfort I do take from RTC point of view is that the ‘Mink’ variant had a change in the spike protein too, and while we still don’t know about vaccine effectiveness, everything I read indicated tests still worked as expected/intended at the same accuracy as previously. My thoughts are that it is more the use case that may bring the RTC undone, though if that came to pass it would mean the vaccine is not effective, and so we would be back on this merry-go-round for another year, and antigen testing would go back to the number one tool to fight COVID. Horrible for the human race, though your investment should be sound. IMO, DYOR.