Member Info for B2HS2L

The title of the article I have linked to is :
Why is Germany able to test for coronavirus so much more than the UK?

Its long, but worth it.

Doesn't mention Novacyt, but good solid info about the Germans preparation for Covid-19 type viruses, and why their statistics don't look like anyone else's in Europe or America.

https://reaction.life/why-is-germany-able-to-test-for-coronavirus-so-much-more-than-the-uk/

I'd like to know who's tests the Germans are using, and from how many different manufacturers

This is why nobody can afford to be out of this share for long:
Manufacturing outsourcing update
US sales figures
Further FDA approvals
Further OEM / NHS sales update
News of next UK test kit manufacturing partner
News of a Takeover
News of a Joint Venture
News of an NCYT Antibodies test kit, and distribution of same.
CFDA Approval

You definitely need to minimise the time you spend out of this share, before any of the above RNS issues might land.

As Clint would say, - D'ya feel lucky punk, - well do ya?

Here are the responses to my request for information from Primerdesign support.

1 If I buy a test kit containing 96 tests, is it correct that I can use a maximum of 16 tests at a time in the q16 instrument?
Ans = Yes, but the q16 machine is only compatible with genesig Easy kits which contain 50 reactions. - (I assume that means tests)

2 If I buy a test kit containing 96 tests, is it correct that I can use a maximum of 32 tests at a time in the q32 instrument?
Ans = Yes

3 If I want to use the tests in a compatible instrument:
Applied Biosystems®7500 Real-Time PCR system
Bio-Rad CFX Connect™Real-Time PCR Detection System
Roche® LightCycler 480 II

Do I have to wait longer than 2 hours for a result.
Ans = The ABI, Bio-Rad and Roche machines take 2-3 hours to run the tests.

++++
So the compatible instruments take longer to provide test results than the low capacity Primerdesign q16 and q32 instruments.

I now believe the Govnt sidelined the Primerdesign q32 instrument because in 2 hours you would be provided with 32 test results.

The Govnt should have been researching where in UK the three compatible instruments were located, such that Primerdesign tests could have been run on these instruments, providing high integrity test results.
No time like the present eh? ;)

I have sent the following questions to Primerdesign support.

1 If I buy a test kit containing 96 tests, is it correct that I can use a maximum of 16 tests at a time in the q16 instrument? 2 If I buy a test kit containing 96 tests, is it correct that I can use a maximum of 32 tests at a time in the q32 instrument?

3 If I want to use the tests in a compatible instrument:
Applied Biosystems®7500 Real-Time PCR system
Bio-Rad CFX Connect™Real-Time PCR Detection System
Roche® LightCycler 480 II

Do I have to wait longer than 2 hours for a result .

++++
My thinking if the above is correct, is that the Govnt problem with Primerdesign eqpmnt is that the capacity of the q32 instrument is only 32 tests at time.
So in 2 hrs you will only get 32 test results.

I don't want to assume the time for processing one of our tests in a compatible instrument is 2 hours.

The other instruments have much greater capacity in terms of the number of tests.

Will advise any response

@bobminor
(ex RAF SNCO (aero-engines) - left in 1987 after 12 years) - a sooty no less

If the military can project manage and deliver a 4000 bed hospital in 8 days, Let them takeover the logistics of testing.
Once the logistics is sorted, and those to be tested and how regularly is solved, perhaps we can make sure that :
a Those NHS staff at home can be tested to see if they can return to work
b Regularly test those NHS staff working with Covid-19 patients, else danger of re-infection
c Prioritise the destinations for PPE.

I am sure that a high level decision to distribute the 'war reserve' has been taken, and that is why so much equipment (Look how new it all is) is available for 'Nightingale' hospitals.

This would solve many problems.

What have I missed.
Primerdesign has a £1 Million order to be provided to 8 hospitals.
We know of no other PHE or NHS order.
So why is Primerdesign saying they are delivering kits to 21 hospitals.
This only makes sense if the original 8 is now 21, - else we have another order?
So why is the company saying they are

If you go to the list of FDA EUA approvals you will see that those tests that are able to crank out the most test results per day (regardless of accuracy) were authorised early. That's possibly why we had to wait a long time for the Primerdesign EUA, despite it being the most accurate test of the lot.
I've never understood why the FDA only gave EUA to companies two per day.

Might be worth investigating if there is a subsequent version of this document before anything goes to press or is asked of a govnt minister.

My interpretation is that version 1 of the document is dated 16th March, but the information in
Appendix 8 is valid up to the 6th March.
Reason not known.

Just give Peston the evidence at let him join the dots.

The caption for the photo of the box entering Downing Street reads:

"Two men wearing suits were pictured carrying a box from ThermoFisher – which makes coronavirus tests that give results in four hours – outside Downing Street This Afternoon."
So I am thinking the date is most likely the 17th, unless the photo and part of the story was updated on 18th March.

Found the article I was looking for :
https://www.dailymail.co.uk/news/article-8122983/This-test-suspected-patients-coronavirus.html

17/18.03.2020

That's possibly why Thermo Fisher does not feature in Appendix 8.

https://www.england.nhs.uk/coronavirus/wp-content/uploads/sites/52/2020/03/guidance-and-sop-covid-19-virus-testing-in-nhs-laboratories-v1.pdf

Look at Page 24 of this document. There are two dates mentioned :

Version 1.0 VIRUS TESTING 16 March 2020.

Appendix 8: Testing systems under evaluation by PHE (as of 6 March 2020)

Somewhere I have kept the story of the Thermo Fisher visit to 10 Downing street, and I will provide the date of this visit if I still have it.

Good find Tom, - sounds like the sort of thing that Robert Peston would be interested in..

Thanks for your responses, - should be a good investment.

GLA.

Watched the proactiveinvestors video interview with CEO Richard Marsden.

He states at the end of the trial he will be discussing the findings with British European, American and other regulators to discuss 'what happens next'.

Can I assume SNG001 is a drug or is it a medical device?

One outcome might be a phase 3 trial. Was a phase 3 trial always necessary, or has it never been necessary?

What other outcomes might there be?

He also states that the SNG001 trial that started in Southampton this week is due to finish in around 8 weeks.

Is that the latest estimate of end of trial please?

TRX RNS 04.06.2019 - Secures Credit Facilities of up to $20m:

"Tissue Regenix Group (AIM:TRX) ("Tissue Regenix", or the "Company" and together with its subsidiaries, the "Group"), the regenerative medical devices company, announces that it has and certain of its subsidiaries have unconditionally entered into agreements with MidCap Financial Trust ("MidCap Financial") to access a revolving credit facility and a term loan credit facility (the "Facilities") of up to $20 million. Funding of $10.5 million is initially available to the Group, of which it plans to draw down an initial $7.5 million immediately.

Use of Proceeds

The initial net proceeds of the Facilities and any further funding drawn down in due course, will be used to invest in additional capital expenditure to sustain future business growth, generate further clinical and health economic real world data to support brand differentiation within dCELL and BioRinse, and for general corporate and working capital purposes."
++++
So the need in June 2019 when they had considerably more working capital than they have now, was $20 Million.

Truthsearcher, you are completely correct.

So one of these options is true:

1 TRX applied for a drawdown and met with an outright rejection, hence much activity trying to find further finance.
2 TRX applied for a drawdown, MidCap refused, but provided details of another unacceptable loan,
hence much activity trying to find further finance.
3 TRX has not applied for a drawdown, because it wants to replace the MidCap loan with another.
(IMO a placing is not viable at present).

Recall that the last CFO left the company days after the MidCap loan was restructured last November, and I believe that deal has been unacceptable to the board ever since.

Whichever, the shareholder only sees loan discussion activity.

If TRX are unsuccessful in finding the loan they want, then the board might want to break up the company and sell off the individual parts to highest bidder, (patents and all). Of course they could find a buyer, which is just what Jonathan Glenn has just done successfully at Consort Medical, lining his pockets nicely at £10.10 / share.

We should give Jonathan Glenn time to work on the discussions mentioned in the RNS.

I happen to think option 3 is true.

Discussions about selling off parts /all of the company might also be taking place, but WTFDIK.