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Portfolio company, PDS Biotechnology Corp, announces updated survival data from the Phase 2 clinical trial investigating the triple combination of PDS0101, PDS0301 (IL-12 antibody-drug conjugate) and an investigational immune checkpoint inhibitor in two groups of advanced cancer patients with various types of human papillomavirus 16-positive cancers. Says 75% of immune checkpoint inhibitor naïve patients remain alive at 36 months. In the ICI resistant group, the 12-month OS rate was 72% and the triple combination achieved a median OS of approximately 20 months.
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By Jeremy Cutler, Alliance News reporter
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